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Protein Overview: EG11921

General Information:
Name(s) found: rluF / EG11921 [EcoGene]
Description(s) found:
Found 6 descriptions.
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  • 23S rRNA pseudouridine(2604) synthase / 23S rRNA pseudouridine(2604) synthase [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 290 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: enzyme-directed rRNA pseudouridine synthesis [IMPLink to PubMed article]
    Molecular Function: RNA binding [IEA]
    pseudouridine synthase activity [IEA][IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLPDSSVRLN KYISESGICS RREADRYIEQ GNVFLNGKRA TIGDQVKPGD VVKVNGQLIE  60
   61 PREAEDLVLI ALNKPVGIVS TTEDGERDNI VDFVNHSKRV FPIGRLDKDS QGLIFLTNHG 120
  121 DLVNKILRAG NDHEKEYLVT VDKPITEEFI RGMSAGVPIL GTVTKKCKVK KEAPFVFRIT 180
  181 LVQGLNRQIR RMCEHFGYEV KKLERTRIMN VSLSGIPLGE WRDLTDDELI DLFKLIENSS 240
  241 SEVKPKAKAK PKTAGIKRPV VKMEKTAEKG GRPASNGKRF TSPGRKKKGR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..218] PSI-BLAST 55.221849 Ribosomal small subunit pseudouridine 516 synthase RsuA; Pseudouridine synthase RsuA N-terminal domain
    2 View Details [219..290] PSI-BLAST 50.522879 No description for 2gmlA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • pseudouridine synthase activity
    		•  5.60483019625575 bayes_pls_golite062009
  • intramolecular transferase activity
    		•  4.62815459483632 bayes_pls_golite062009
  • isomerase activity
    		•  3.43067391737824 bayes_pls_golite062009
  • catalytic activity
    		•  2.39224964671205 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.93805098366683 bayes_pls_golite062009
  • structural molecule activity
    		•  1.65902435754631 bayes_pls_golite062009
  • RNA binding
    		•  0.351909066993469 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle