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Protein Overview: EG10768

General Information:
Name(s) found: proB / EG10768 [EcoGene]
Description(s) found:
Found 5 descriptions.
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  • gamma-glutamate kinase / Glutamate 5-kinase, proline biosynthesis; dimeric; feedback inhibition by proline [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 367 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    Biological Process: proline biosynthetic process [IEA][IMPLink to PubMed article]
    Molecular Function: nucleotide binding [IEA]
    magnesium ion binding [IDALink to PubMed articleLink to PubMed articleLink to PubMed article]
    ATP binding [IEA]
    RNA binding [IEA]
    glutamate 5-kinase activity [IDALink to PubMed articleLink to PubMed articleLink to PubMed article][IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDSQTLVVK LGTSVLTGGS RRLNRAHIVE LVRQCAQLHA AGHRIVIVTS GAIAAGREHL  60
   61 GYPELPATIA SKQLLAAVGQ SRLIQLWEQL FSIYGIHVGQ MLLTRADMED RERFLNARDT 120
  121 LRALLDNNIV PVINENDAVA TAEIKVGDND NLSALAAILA GADKLLLLTD QKGLYTADPR 180
  181 SNPQAELIKD VYGIDDALRA IAGDSVSGLG TGGMSTKLQA ADVACRAGID TIIAAGSKPG 240
  241 VIGDVMEGIS VGTLFHAQAT PLENRKRWIF GAPPAGEITV DEGATAAILE RGSSLLPKGI 300
  301 KSVTGNFSRG EVIRICNLEG RDIAHGVSRY NSDALRRIAG HHSQEIDAIL GYEYGPVAVH 360
  361 RDDMITR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..367] PSI-BLAST 96.522879 No description for 2j5tA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle