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Protein Overview: EG12712

General Information:
Name(s) found: luxS / EG12712 [EcoGene]
Description(s) found:
Found 5 descriptions.
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  • S-ribosylhomocysteine lyase / S-ribosylhomocysteine lyase, autoinducer 2 (AI-2) synthesis; functions in quorum sensing; acid-inducible [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 171 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: L-methionine biosynthetic process from S-adenosylmethionine [IDALink to PubMed article]
    cell-cell signaling involved in quorum sensing [IMPLink to PubMed article]
    generation of a signal involved in cell-cell signaling [IDALink to PubMed article][IMPLink to PubMed article]
    Molecular Function: S-ribosylhomocysteine lyase activity [IDALink to PubMed article][IEA][ISSLink to PubMed article]
    protein binding [IPILink to PubMed article]
    metal ion binding [IEA]
    iron ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLLDSFTVD HTRMEAPAVR VAKTMNTPHG DAITVFDLRF CVPNKEVMPE RGIHTLEHLF  60
   61 AGFMRNHLNG NGVEIIDISP MGCRTGFYMS LIGTPDEQRV ADAWKAAMED VLKVQDQNQI 120
  121 PELNVYQCGT YQMHSLQEAQ DIARSILERD VRINSNEELA LPKEKLQELH I

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..171] PSI-BLAST 80.522879 Autoinducer-2 production protein LuxS

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • S-ribosylhomocysteine lyase activity
    		•  1.74759627448878 bayes_pls_golite062009
  • quorum sensing signal generator activity
    		•  1.39649645139585 bayes_pls_golite062009
  • quorum sensing response regulator activity
    		•  1.39649645139585 bayes_pls_golite062009
  • catalytic activity
    		•  0.00996887145100289 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle