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Protein Overview: EG13091

General Information:
Name(s) found: rppH / EG13091 [EcoGene]
Description(s) found:
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  • RNA pyrophosphohydrolase / RNA pyrophosphohydrolase, destabilizes primary transcripts [EcoGene]
  • nucleotide hydrolase [Escherichia coli K12] [nr-271106-contam.fasta]
  • ORF_f176 [nr-271106-contam.fasta]
  • dinucleoside polyphosphate hydrolase [Escherichia coli K12] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • nucleotide hydrolase [Escherichia coli str. K-12 substr. MG1655] [Ecoli-contam-Dam1-Mind-COMA-MBP-110.fasta]
  • RNA pyrophosphohydrolase [Escherichia coli str. K-12 substr. MG1655] [c_elegans-WS236-ecoli-05Mar2013-contam.fasta]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 176 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: RNA destabilization [IMPLink to PubMed article]
    mRNA catabolic process [IMPLink to PubMed article]
    Molecular Function: magnesium ion binding [IEA]
    zinc ion binding [IEA]
    RNA pyrophosphohydrolase activity [IDALink to PubMed article]
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [IDALink to PubMed article]
    manganese ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIDDDGYRPN VGIVICNRQG QVMWARRFGQ HSWQFPQGGI NPGESAEQAM YRELFEEVGL  60
   61 SRKDVRILAS TRNWLRYKLP KRLVRWDTKP VCIGQKQKWF LLQLVSGDAE INMQTSSTPE 120
  121 FDGWRWVSYW YPVRQVVSFK RDVYRRVMKE FASVVMSLQE NTPKPQNASA YRRKRG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..176] PSI-BLAST 27.39794 Diadenosine tetraphosphate hydrolase (Ap4A hydrolase)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity
    		•  1.86826130963189 bayes_pls_golite062009
  • catalytic activity
    		•  1.86119802438676 bayes_pls_golite062009
  • RNA pyrophosphohydrolase activity
    		•  0.681788425915311 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.544115189438 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.54377405132398 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.468153646537656 bayes_pls_golite062009
  • binding
    		•  0.0581982566440131 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle