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Protein Overview: EG13238

General Information:
Name(s) found: cobU / EG13238 [EcoGene]
Description(s) found:
Found 5 descriptions.
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  • cobinamide kinase and cobinamide phosphate guanylyltransferase / Partial cobalamin biosynthesis pathway present in E. coli [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 181 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: cobalamin biosynthetic process [IEA][IGILink to PubMed article]
    Molecular Function: GTP binding [IEA]
    nucleotide binding [IEA]
    ATP binding [IEA]
    catalytic activity [IEA]
    cobinamide kinase activity [ISSLink to PubMed article]
    adenosylcobinamide kinase activity [IEA]
    transferase activity [IEA]
    adenosylcobinamide-phosphate guanylyltransferase activity [IEA]
    kinase activity [IEA]
    cobinamide phosphate guanylyltransferase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMILVTGGAR SGKSRHAEAL IGDSSQVLYI ATSQILDDEM AARIEHHRQG RPEHWRTVER  60
   61 WQHLDELIHA DINPNEVVLL ECVTTMVTNL LFDYGGDKDP DEWDYQAMEQ AINAEIQSLI 120
  121 AACQRCPAKV VLVTNEVGMG IVPESRLARH FRDIAGRVNQ QLAAAANEVW LVVSGIGVKI 180
  181 K

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..181] PSI-BLAST 63.0 Adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase CobU

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.37148167194523 bayes_pls_golite062009
  • cob(I)yrinic acid a,c-diamide adenosyltransferase activity
    		•  0.0388346549390599 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle