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Protein Overview: EG11435

General Information:
Name(s) found: marR / EG11435 [EcoGene]
Description(s) found:
Found 4 descriptions.
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  • transcriptional repressor of multiple antibiotic resistance / Transcription repressor of multiple antibiotic resistance; copper-sensitive protein; resistance to tetracycline and chloramphenicol; dimeric [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 144 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEA]
    Biological Process: transcription [IEA]
    response to antibiotic [IEA]
    regulation of transcription, DNA-dependent [IEA]
    Molecular Function: DNA binding [IEA]
    transcription factor activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSTSDLFNE IIPLGRLIHM VNQKKDRLLN EYLSPLDITA AQFKVLCSIR CAACITPVEL  60
   61 KKVLSVDLGA LTRMLDRLVC KGWVERLPNP NDKRGVLVKL TTGGAAICEQ CHQLVGQDLH 120
  121 QELTKNLTAD EVATLEYLLK KVLP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..144] PSI-BLAST 27.0 Multiple antibiotic resistance repressor, MarR

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.835523092977445 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.4843036104266 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.37117756729668 bayes_pls_golite062009
  • DNA binding
    		•  0.3118855114645 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle