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Protein Overview: EG11358

General Information:
Name(s) found: murA / EG11358 [EcoGene]
Description(s) found:
Found 5 descriptions.
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  • UDP-N-acetylglucosamine 1-carboxyvinyltransferase / UDP-N-acetylglucosamine enoylpyruvyl transferase; fosfomycin resistance [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 419 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    Biological Process: cell division [IEA]
    regulation of cell shape [IEA]
    peptidoglycan biosynthetic process [IEA]
    cellular cell wall organization [IEA]
    UDP-N-acetylgalactosamine biosynthetic process [IEA]
    cell cycle [IEA]
    Molecular Function: UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity [IDALink to PubMed articleLink to PubMed article][IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKFRVQGPT KLQGEVTISG AKNAALPILF AALLAEEPVE IQNVPKLKDV DTSMKLLSQL  60
   61 GAKVERNGSV HIDARDVNVF CAPYDLVKTM RASIWALGPL VARFGQGQVS LPGGCTIGAR 120
  121 PVDLHISGLE QLGATIKLEE GYVKASVDGR LKGAHIVMDK VSVGATVTIM CAATLAEGTT 180
  181 IIENAAREPE IVDTANFLIT LGAKISGQGT DRIVIEGVER LGGGVYRVLP DRIETGTFLV 240
  241 AAAISRGKII CRNAQPDTLD AVLAKLRDAG ADIEVGEDWI SLDMHGKRPK AVNVRTAPHP 300
  301 AFPTDMQAQF TLLNLVAEGT GFITETVFEN RFMHVPELSR MGAHAEIESN TVICHGVEKL 360
  361 SGAQVMATDL RASASLVLAG CIAEGTTVVD RIYHIDRGYE RIEDKLRALG ANIERVKGE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..419] PSI-BLAST 147.0 UDP-N-acetylglucosamine enolpyruvyl transferase (EPT, MurA, MurZ)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 3-phosphoshikimate 1-carboxyvinyltransferase activity
    		•  4.6363282422962 bayes_pls_golite062009
  • UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
    		•  3.87711259634234 bayes_pls_golite062009
  • catalytic activity
    		•  2.91733519293428 bayes_pls_golite062009
  • transferase activity, transferring alkyl or aryl (other than methyl) groups
    		•  2.15049036934665 bayes_pls_golite062009
  • transferase activity
    		•  1.9014276549152 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.88

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle