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Protein Overview: EG11070

General Information:
Name(s) found: dsbC / EG11070 [EcoGene]
Description(s) found:
Found 4 descriptions.
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  • protein disulfide isomerase II / Disulfide bond isomerase, periplasmic; chaperone; activated by DsbD; homodimeric [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 236 amino acids

    Gene Ontology:
    Cellular Component: periplasmic space [IEA][RCALink to PubMed article]
    Biological Process: cell redox homeostasis [IEA]
    Molecular Function: protein disulfide isomerase activity [IDALink to PubMed article][IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKGFMLFTL LAAFSGFAQA DDAAIQQTLA KMGIKSSDIQ PAPVAGMKTV LTNSGVLYIT  60
   61 DDGKHIIQGP MYDVSGTAPV NVTNKMLLKQ LNALEKEMIV YKAPQEKHVI TVFTDITCGY 120
  121 CHKLHEQMAD YNALGITVRY LAFPRQGLDS DAEKEMKAIW CAKDKNKAFD DVMAGKSVAP 180
  181 ASCDVDIADH YALGVQLGVS GTPAVVLSNG TLVPGYQPPK EMKEFLDEHQ KMTSGK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..236] PSI-BLAST 55.30103 Disulfide bond isomerase, DsbC, C-terminal domain; Disulfide bond isomerase, DsbC, N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein disulfide isomerase activity
    		•  1.48801287843472 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, transposing S-S bonds
    		•  1.48801287843472 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, interconverting keto- and enol-groups
    		•  1.37876060576659 bayes_pls_golite062009
  • catalytic activity
    		•  1.04263226837398 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors
    		•  0.25957505753521 bayes_pls_golite062009
  • isomerase activity
    		•  0.24662332270942 bayes_pls_golite062009
  • disulfide oxidoreductase activity
    		•  0.22354310938224 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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