YRC Public Data Repository - Protein Structure Prediction

Protein:	EG11070
Organism:	Escherichia coli str. K-12 substr. MG1655
Length:	236 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EG11070.

Description	E-value	Query Range	Subject Range
gi\|110616344, gi... - gi\|110806796\|ref\|YP_690316.1\| thiol:disulfide interchange protein DsbC [Shigella flexneri 5 str. 840... gi\|194431750, gi... - gi\|194431750\|ref\|ZP_03064041.1\| thiol:disulfide interchange protein DsbC [Shigella dysenteriae 1012]... gi\|215266265, gi... - gi\|215488193\|ref\|YP_002330624.1\| thiol:disulfide interchange protein DsbC [Escherichia coli O127:H6 ... gi\|24114147, gi\|... - gi\|24114147\|ref\|NP_708657.1\| thiol:disulfide interchange protein DsbC [Shigella flexneri 2a str. 301... gi\|30042462, gi\|... - gi\|30064205\|ref\|NP_838376.1\| thiol:disulfide interchange protein DsbC [Shigella flexneri 2a str. 245... gi\|170682633, gi... - gi\|170682633\|ref\|YP_001745046.1\| thiol:disulfide interchange protein DsbC [Escherichia coli SMS-3-5]...	237.0	[0..1]	[236..1]
gi\|82778341, gi\|... - gi\|82778341\|ref\|YP_404690.1\| thiol:disulfide interchange protein DsbC [Shigella dysenteriae Sd197], ...	236.0	[0..1]	[236..1]
gi\|26109716, gi\|... - gi\|26249308\|ref\|NP_755348.1\| thiol:disulfide interchange protein DsbC [Escherichia coli CFT073], gi\|... gi\|237706463, gi... - gi\|237706463\|ref\|ZP_04536944.1\| thiol:disulfide interchange protein DsbC [Escherichia sp. 3_2_53FAA]... gi\|117625124, gi... - gi\|117625124\|ref\|YP_854112.1\| thiol:disulfide interchange protein DsbC [Escherichia coli APEC O1], g... gi\|227888442, gi... - gi\|227888442\|ref\|ZP_04006247.1\| protein disulfide-isomerase [Escherichia coli 83972], gi\|227834711\|g... gi\|218428582, gi... - gi\|218691018\|ref\|YP_002399230.1\| thiol:disulfide interchange protein DsbC [Escherichia coli ED1a], g... gi\|218366655, gi... - gi\|218559886\|ref\|YP_002392799.1\| thiol:disulfide interchange protein DsbC [Escherichia coli S88], gi... gi\|91212271, gi\|... - gi\|91212271\|ref\|YP_542257.1\| thiol:disulfide interchange protein DsbC [Escherichia coli UTI89], gi\|9...	236.0	[0..1]	[236..1]
gi\|254162805, gi... - gi\|254162805\|ref\|YP_003045913.1\| protein disulfide isomerase II [Escherichia coli B str. REL606], gi... gi\|75515324, gi\|... - gi\|75515324\|ref\|ZP_00737508.1\| COG1651: Protein-disulfide isomerase [Escherichia coli 53638], gi\|188... gi\|157068033, gi... - gi\|75196845\|ref\|ZP_00706915.1\| COG1651: Protein-disulfide isomerase [Escherichia coli HS], gi\|157162... gi\|254289565, gi... - gi\|254289565\|ref\|YP_003055313.1\| protein disulfide isomerase II [Escherichia coli BL21(DE3)], gi\|253... gi\|251786151, gi... - gi\|251786151\|ref\|YP_003000455.1\| hypothetical protein B21_02688 [Escherichia coli BL21], gi\|24237842...	235.0	[0..1]	[236..1]
gi\|209913606, gi... - gi\|209920347\|ref\|YP_002294431.1\| thiol:disulfide interchange protein DsbC [Escherichia coli SE11], g... gi\|218696488, gi... - gi\|218696488\|ref\|YP_002404155.1\| thiol:disulfide interchange protein DsbC [Escherichia coli 55989], ... gi\|193063526, gi... - gi\|75258492\|ref\|ZP_00729914.1\| COG1651: Protein-disulfide isomerase [Escherichia coli E22], gi\|19306... gi\|75212493, gi\|... - gi\|75212493\|ref\|ZP_00712517.1\| COG1651: Protein-disulfide isomerase [Escherichia coli B171], gi\|1944...	235.0	[0..1]	[236..1]
gi\|157155887, gi... - gi\|75187609\|ref\|ZP_00700876.1\| COG1651: Protein-disulfide isomerase [Escherichia coli E24377A], gi\|1...	235.0	[0..1]	[236..1]
gi\|15803429, gi\|... - gi\|15803429\|ref\|NP_289462.1\| thiol:disulfide interchange protein DsbC [Escherichia coli O157:H7 EDL9... gi\|25292653 - gi\|25292653\|pir\|\|A85945 protein disulfide isomerase II [imported] - Escherichia coli (strain O157:H7...	234.0	[0..1]	[236..1]
gi\|73856928, gi\|... - gi\|74313451\|ref\|YP_311870.1\| thiol:disulfide interchange protein DsbC [Shigella sonnei Ss046], gi\|73...	234.0	[0..1]	[236..1]
gi\|191173221, gi... - gi\|75239237\|ref\|ZP_00723210.1\| COG1651: Protein-disulfide isomerase [Escherichia coli F11], gi\|19117... gi\|110344633, gi... - gi\|110643041\|ref\|YP_670771.1\| thiol:disulfide interchange protein DsbC [Escherichia coli 536], gi\|11...	234.0	[0..1]	[236..1]
gi\|187731623, gi... - gi\|75178786\|ref\|ZP_00698822.1\| COG1651: Protein-disulfide isomerase [Shigella boydii BS512], gi\|1877... gi\|82545484, gi\|... - gi\|82545484\|ref\|YP_409431.1\| thiol:disulfide interchange protein DsbC [Shigella boydii Sb227], gi\|81...	234.0	[0..1]	[235..1]

Back

Predicted Domain #1

Region A:
Residues: [1-236]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKGFMLFTL LAAFSGFAQA DDAAIQQTLA KMGIKSSDIQ PAPVAGMKTV LTNSGVLYIT  60
   61 DDGKHIIQGP MYDVSGTAPV NVTNKMLLKQ LNALEKEMIV YKAPQEKHVI TVFTDITCGY 120
  121 CHKLHEQMAD YNALGITVRY LAFPRQGLDS DAEKEMKAIW CAKDKNKAFD DVMAGKSVAP 180
  181 ASCDVDIADH YALGVQLGVS GTPAVVLSNG TLVPGYQPPK EMKEFLDEHQ KMTSGK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	55.30103
Match:	1eejA
Description:	Disulfide bond isomerase, DsbC, C-terminal domain; Disulfide bond isomerase, DsbC, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein disulfide isomerase activity	1.48801287843472	bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing S-S bonds	1.48801287843472	bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting keto- and enol-groups	1.37876060576659	bayes_pls_golite062009
catalytic activity	1.04263226837398	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	0.25957505753521	bayes_pls_golite062009
isomerase activity	0.24662332270942	bayes_pls_golite062009
disulfide oxidoreductase activity	0.22354310938224	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: