YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: EG10496

General Information:
Name(s) found: ilvD / EG10496 [EcoGene]
Description(s) found:
Found 5 descriptions.
SHOW ALL
  • dihydroxyacid dehydratase / Dihydroxyacid dehydratase; homodimeric [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 616 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: isoleucine biosynthetic process [IDALink to PubMed article][IEA]
    valine biosynthetic process [IDALink to PubMed article][IEA]
    Molecular Function: dihydroxy-acid dehydratase activity [IDALink to PubMed article][IEA]
    metal ion binding [IEA]
    iron ion binding [IEA]
    4 iron, 4 sulfur cluster binding [IEA]
    iron-sulfur cluster binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKYRSATTT HGRNMAGARA LWRATGMTDA DFGKPIIAVV NSFTQFVPGH VHLRDLGKLV  60
   61 AEQIEAAGGV AKEFNTIAVD DGIAMGHGGM LYSLPSRELI ADSVEYMVNA HCADAMVCIS 120
  121 NCDKITPGML MASLRLNIPV IFVSGGPMEA GKTKLSDQII KLDLVDAMIQ GADPKVSDSQ 180
  181 SDQVERSACP TCGSCSGMFT ANSMNCLTEA LGLSQPGNGS LLATHADRKQ LFLNAGKRIV 240
  241 ELTKRYYEQN DESALPRNIA SKAAFENAMT LDIAMGGSTN TVLHLLAAAQ EAEIDFTMSD 300
  301 IDKLSRKVPQ LCKVAPSTQK YHMEDVHRAG GVIGILGELD RAGLLNRDVK NVLGLTLPQT 360
  361 LEQYDVMLTQ DDAVKNMFRA GPAGIRTTQA FSQDCRWDTL DDDRANGCIR SLEHAYSKDG 420
  421 GLAVLYGNFA ENGCIVKTAG VDDSILKFTG PAKVYESQDD AVEAILGGKV VAGDVVVIRY 480
  481 EGPKGGPGMQ EMLYPTSFLK SMGLGKACAL ITDGRFSGGT SGLSIGHVSP EAASGGSIGL 540
  541 IEDGDLIAID IPNRGIQLQV SDAELAARRE AQDARGDKAW TPKNRERQVS FALRAYASLA 600
  601 TSADKGAVRD KSKLGG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..616] PSI-BLAST 171.0 No description for 2gp4A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 3-isopropylmalate dehydratase activity
    		•  5.35660492472618 bayes_pls_golite062009
  • dihydroxy-acid dehydratase activity
    		•  1.86041876362237 bayes_pls_golite062009
  • catalytic activity
    		•  1.61959327305722 bayes_pls_golite062009
  • carbon-oxygen lyase activity
    		•  1.16841092671386 bayes_pls_golite062009
  • hydro-lyase activity
    		•  1.13002130445077 bayes_pls_golite062009
  • lyase activity
    		•  1.11228159918123 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle