Protein Overview: BPI_RAT

General Information:
Name(s) found:	BPI_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|81884471\|sp\|Q6AXU0.1\|BPI_RAT RecName: Full=Bactericidal permeability-increasing protein; Short=BPI; Flags: Precursor [NCBI NR] gi\|51854219\|ref\|NP_001004079.1\| bactericidal/permeability-increasing protein [Rattus norvegicus] [NCBI NR] gi\|50925869\|gb\|AAH79318.1\| Bactericidal/permeability-increasing protein [Rattus norvegicus] [NCBI NR] Bactericidal permeability-increasing protein OS=Rattus norvegicus GN=Bpi PE=2 SV=1 [Swiss-Prot] Bactericidal/permeability-increasing protein [Rattus norvegicus]gi\|51854219\|ref\|NP_001004079.1\| bactericidal/permeability-increasing protein [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Bactericidal/permeability-increasing protein [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] bactericidal/permeability-increasing protein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Bactericidal/permeability-increasing protein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 BACTERICIDAL/PERMEABILITY-INCREASING PROTEIN [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] bactericidal/permeability-increasing protein precursor [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Bactericidal permeability-increasing protein OS=Rattus norvegicus GN=Bpi [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	482 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [UNKNOWN][IDA] membrane [IEA] extracellular region [IEA]
Biological Process:	negative regulation of interleukin-6 production [UNKNOWN][IEA] immune response [IDA] negative regulation of macrophage activation [UNKNOWN][IEA] negative regulation of interleukin-8 production [UNKNOWN][IEA] defense response to bacterium [IDA] negative regulation of tumor necrosis factor production [UNKNOWN][IEA]
Molecular Function:	lipid binding [TAS] Gram-negative bacterial cell surface binding [IDA] lipopolysaccharide binding [UNKNOWN][IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAWGPDNVRK WSSLALLAIV GTALTAATDP GFVARISQKG LDFVCQESMV ELQKELLAIS  60
   61 IPDFSGDFKI KHLGKGTYEF YSMAVEGFHI PDPQIKLLPS DGLQLSITSA SIKISGRWKY 120
  121 RKNILKASGN FQLSIQGVSI IADLILGNDP SGRITITCST CDSHINSVRI KVSGSMLGWL 180
  181 IQLFHRKIET SLKKTIYKKI CKIVRNSVSA KLQPYVKTLP VVAKVDDITS IDYSLLAPPM 240
  241 TTDKFLEGQL RGEFFWRGHH GPFPAVPPVM NILPNNNYMV CMGISDYFFN TAEFAYQESE 300
  301 TLKITLRDQL LAKDARYHLN TDFLKTFLPE VAKKFPSMGL QLLISAPLFA HLNIQPSGLS 360
  361 LSPNLETRAF VVLPNSSLIP LFLLGMKTNA SLEVNAMKNR LIGEMKLGRL LLELKQSNFG 420
  421 SFKVELLEDV INYLMSTMVL PKINEKLRRG FPLPLPAGIQ LINSILYSSQ NFLLLEADLH 480
  481 RT

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: BPI_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: