Protein Overview: UBR2_MOUSE

General Information:
Name(s) found:	UBR2_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|73622074\|sp\|Q6WKZ8.2\|UBR2_MOUSE RecName: Full=E3 ubiquitin-protein ligase UBR2; AltName: Full=N-recognin-2; AltName: Full=Ubiquitin-protein ligase E3-alpha-2; AltName: Full=Ubiquitin-protein ligase E3-alpha-II [NCBI NR] gi\|58615693\|ref\|NP_666190.2\| ubiquitin protein ligase E3 component n-recognin 2 [Mus musculus] [NCBI NR] ref\|XP_358323.2\| ubiquitin ligase E3 alpha-II [Mus musculus] [NCBI NR] gi\|49522661\|gb\|AAH75642.1\| Ubiquitin protein ligase E3 component n-recognin 2 [Mus musculus] [NCBI NR] E3 ubiquitin-protein ligase UBR2 OS=Mus musculus GN=Ubr2 PE=1 SV=2 [Swiss-Prot] ubiquitin ligase E3 alpha-II [Mus musculus]gi\|49522661\|gb\|AAH75642.1\| E130209G04Rik protein [Mus musculus] [nrdb_11152004_Chlamydomonas] Tax_Id=10090 Splice Isoform 1 of Ubiquitin-protein ligase E3 component N-recognin-2 [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] ubiquitin protein ligase E3 component n-recognin 2 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] E3 ubiquitin-protein ligase UBR2 (N-recognin-2) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3-alpha-II) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Ubiquitin protein ligase E3 component n-recognin 2 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Ubr2 Isoform 1 of E3 ubiquitin-protein ligase UBR2 [mouse-ipi-250309-contam.fasta] Ubiquitin-protein ligase E3 component N-recognin-2 (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3-alpha-II) [nr-271106-contam.fasta] Tax_Id=10090 Gene_Symbol=Ubr2 Isoform 1 of E3 ubiquitin-protein ligase UBR2 ENSMUSG00000023977 IPI00468701 IPI00648087 IPI00405095 [IPIxENS.MOUSE_plus_REVERSE.fasta] E3 ubiquitin-protein ligase UBR2 isoform 1 [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00468701.2\|SWISS-PROT:Q6WKZ8-1\|TREMBL:Q3UHE0\|ENSEMBL:ENSMUSP00000075230;ENSMUSP00000108963\|REFSEQ:NP_666190 Tax_Id=10090 Gene_Symbol=Ubr2 Isoform 1 of E3 ubiquitin-protein ligase UBR2 [ipi.MOUSE.fasta.20090209] Isoform 1 of E3 ubiquitin-protein ligase UBR2 OS=Mus musculus GN=Ubr2 [011711_HMR.fasta] sp\|Q6WKZ8\|UBR2_MOUSE E3 ubiquitin-protein ligase UBR2 OS=Mus musculus GN=Ubr2 PE=1 SV=2 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	1755 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA] ubiquitin ligase complex [IGI]
Biological Process:	protein catabolic process [IEA] spermatogenesis [IMP] male meiosis I [IMP] ubiquitin-dependent protein catabolic process [IDA]
Molecular Function:	ubiquitin-protein ligase activity [IDA][IGI] zinc ion binding [IEA] protein binding [IPI] metal ion binding [IEA] ligase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASEMEPEVQ AIDRSLLECS AEEIAGRWLQ ATDLNREVYQ HLAHCVPKIY CRGPNPFPQK  60
   61 EDTLAQHILL GPMEWYICAE DPALGFPKLE QANKPSHLCG RVFKVGEPTY SCRDCAVDPT 120
  121 CVLCMECFLG SIHRDHRYRM TTSGGGGFCD CGDTEAWKEG PYCQKHKLSS SEVVEEEDPL 180
  181 VHLSEDVIAR TYNIFAIMFR YAVDILTWEK ESELPEDLEV AEKSDTYYCM LFNDEVHTYE 240
  241 QVIYTLQKAV NCTQKEAIGF ATTVDRDGRR SVRYGDFQYC DQAKTVIVRN TSRQTKPLKV 300
  301 QVMHSSVAAH QNFGLKALSW LGSVIGYSDG LRRILCQVGL QEGPDGENSS LVDRLMLNDS 360
  361 KLWKGARSVY HQLFMSSLLM DLKYKKLFAL RFAKNYRQLQ RDFMEDDHER AVSVTALSVQ 420
  421 FFTAPTLARM LLTEENLMTV IIKAFMDHLK HRDAQGRFQF ERYTALQAFK FRRVQSLILD 480
  481 LKYVLISKPT EWSDELRQKF LQGFDAFLEL LKCMQGMDPI TRQVGQHIEM EPEWEAAFTL 540
  541 QMKLTHVISM VQDWCALDEK VLIEAYKKCL AVLTQCHGGF TDGEQPITLS ICGHSVETIR 600
  601 YCVSQEKVSI HLPISRLLAG LHVLLSKSEV AYKFPELLPL SELSPPMLIE HPLRCLVLCA 660
  661 QVHAGMWRRN GFSLVNQIYY YHNVKCRREM FDKDIVMLQT GVSMMDPNHF LMIMLSRFEL 720
  721 YQLFSTPDYG KRFSSEVTHK DVVQQNNTLI EEMLYLIIML VGERFNPGVG QVAATDEIKR 780
  781 EIIHQLSIKP MAHSELVKSL PEDENKETGM ESVIESVAHF KKPGLTGRGM YELKPECAKE 840
  841 FNLYFYHFSR AEQSKAEEAQ RKLKRENKED TALPPPALPP FCPLFASLVN ILQCDVMLYI 900
  901 MGTILQWAVE HHGSAWSESM LQRVLHLIGM ALQEEKHHLE NAVEGHVQTF TFTQKISKPG 960
  961 DAPHNSPSIL AMLETLQNAP SLEAHKDMIR WLLKMFNAIK KIRECSSSSP VAEAEGTIME1020
 1021 ESSRDKDKAE RKRKAEIARL RREKIMAQMS EMQRHFIDEN KELFQQTLEL DTSASATLDS1080
 1081 SPPVSDAALT ALGPAQTQVP EPRQFVTCIL CQEEQEVTVG SRAMVLAAFV QRSTVLSKDR1140
 1141 TKTIADPEKY DPLFMHPDLS CGTHTGSCGH VMHAHCWQRY FDSVQAKEQR RQQRLRLHTS1200
 1201 YDVENGEFLC PLCECLSNTV IPLLLPPRSI LSRRLNFSDQ PDLAQWTRAV TQQIKVVQML1260
 1261 RRKHNAADTS SSEDTEAMNI IPIPEGFRPD FYPRNPYSDS IKEMLTTFGT AAYKVGLKVH1320
 1321 PNEGDPRVPI LCWGTCAYTI QSIERILSDE EKPVFGPLPC RLDDCLRSLT RFAAAHWTVA1380
 1381 LLPVVQGHFC KLFASLVPSD SYEDLPCILD IDMFHLLVGL VLAFPALQCQ DFSGSSLATG1440
 1441 DLHIFHLVTM AHIVQILLTS CTEENGMDQE NPTGEEELAI LSLHKTLHQY TGSALKEAPS1500
 1501 GWHLWRSVRA AIMPFLKCSA LFFHYLNGVP APPDLQVSGT SHFEHLCNYL SLPTNLIHLF1560
 1561 QENSDIMNSL IESWCQNSEV KRYLNGERGA ISYPRGANKL IDLPEDYSSL INQASNFSCP1620
 1621 KSGGDKSRAP TLCLVCGSLL CSQSYCCQAE LEGEDVGACT AHTYSCGSGA GIFLRVRECQ1680
 1681 VLFLAGKTKG CFYSPPYLDD YGETDQGLRR GNPLHLCQER FRKIQKLWQQ HSITEEIGHA1740
 1741 QEANQTLVGI DWQHL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.89

Protein Overview: UBR2_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: