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Protein Overview: TYDP1_ARATH

General Information:
Name(s) found: TYDP1_ARATH [Swiss-Prot]
Description(s) found:
Found 9 descriptions.
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  • Tyrosyl-DNA phosphodiesterase 1 OS=Arabidopsis thaliana GN=TDP1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 605 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    Biological Process: DNA repair [IEA]
    Molecular Function: phosphoric diester hydrolase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAHSQVAYLI PLKADLKEDN SSPRITLSEG PNIIGRGNVS IVDKRLSRKH ITIIVSTSGS  60
   61 ASLSVDGTNP VVIRSSGDGE RKKVKPSEEV SVCNDDLIEL IPGHHFFKLV LLNGRAAKKA 120
  121 RKAEDDVEAI RRFCPPNEKL PSTFRLLSVD ALPDWANTSC VSINDVIEGD VVAAILSNYM 180
  181 VDIDWLMSAC PKLANIPQVM VIHGEGDGRQ EYIQRKKPAN WILHKPRLPI SFGTHHSKAI 240
  241 FLVYPRGVRV VVHTANLIHV DWNNKSQGLW MQDFPWKDDD KDPPKGCGFE GDLIDYLNVL 300
  301 KWPEFTANLP GRGNVKINAA FFKKFDYSDA TVRLIASVPG YHTGFNLNKW GHMKLRTILQ 360
  361 ECIFDREFRR SPLIYQFSSL GSLDEKWLAE FGNSLSSGIT EDKTPLGPGD SLIIWPTVED 420
  421 VRCSLEGYAA GNAIPSPLKN VEKPFLKKYW ARWKADHSAR GRAMPHIKTF TRYNDQKIAW 480
  481 FLLTSSNLSK AAWGALQKNN SQLMIRSYEL GVLFLPSPIK TQGCVFSCTE SNPSVMKAKQ 540
  541 ETKDEVEKRS KLVTMTWQGD RDLPEIISLP VPYQLPPKPY SPEDVPWSWD RGYSKKDVYG 600
  601 QVWPR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..128] FFAS03 3.24 Molecular architecture of mammalian polynucleotide kinase, a DNA repair enzyme
    2 View Details [129..605] PSI-BLAST 159.0 human Tyrosyl DNA phosphodiesterase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.798082397599655 bayes_pls_golite062009
  • protein binding
    		•  0.37317243448195 bayes_pls_golite062009
    2
    Term Confidence Notes
  • catalytic activity
    		•  0.762303478549781 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle