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Protein Overview: PDE6_DICDI

General Information:
Name(s) found: PDE6_DICDI [Swiss-Prot]
Description(s) found:
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  • gi|74865753|sp|Q8MM62.1|PDE6_DICDI RecName: Full=cAMP/cGMP-dependent 3',5'-cAMP/cGMP phosphodiesterase B; AltName: Full=Phosphodiesterase 6; Short=DdPDE6; AltName: Full=Phosphodiesterase E; AltName: Full=Cyclic GMP-binding protein B [NCBI NR]
  • gi|60471353|gb|EAL69313.1| hypothetical protein DDB0185220 [Dictyostelium discoideum] [NCBI NR]
  • gi|42733833|gb|AAS38751.1| similar to Leptospira interrogans serovar lai str. 56601. CAMP-dependent protein kinase regulatory chain [Dictyostelium discoideum] [NCBI NR]
  • gi|21069537|gb|AAM34040.1|AF481922_1 cAMP/cGMP-stimulated cAMP/cGMP phosphodiesterase [Dictyostelium discoideum] [NCBI NR]
  • gi|18031841|gb|AAL06060.1| cAMP phosphodiesterase [Dictyostelium discoideum] [NCBI NR]
  • cAMP/cGMP-dependent 3',5'-cAMP/cGMP phosphodiesterase B OS=Dictyostelium discoideum GN=pdeE PE=1 SV=1 [Swiss-Prot]
  • cAMP phosphodiesterase [Dictyostelium discoideum]gi|21069537|gb|AAM34040.1| cAMP/cGMP-stimulated cAMP/cGMP phosphodiesterase [Dictyostelium discoideum]gi|42733833|gb|AAS38751.1| similar to Leptospira interrogans serovar lai str. 56601. CAMP-dependent pr [nrdb_11152004_Chlamydomonas]
  • |Protein| gene: pdeE on chromosome: 2 position 6290009 to 6293579 [dicty_predictions_protein.fasta]
  • cAMP phosphodiesterase [Dictyostelium discoideum] [nr-271106-contam.fasta]
  • similar to Leptospira interrogans serovar lai str. 56601. CAMP-dependent protein kinase regulatory chain [Dictyostelium discoideum] [nr-271106-contam.fasta]
  • cAMP/cGMP-stimulated cAMP/cGMP phosphodiesterase [Dictyostelium discoideum] [nr-271106-contam.fasta]
    • Organism: Dictyostelium discoideum
    Length: 1096 amino acids

    Gene Ontology:
    Cellular Component: intracellular [TAS]
    Biological Process: cGMP catabolic process [TAS]
    cAMP catabolic process [TAS]
    Molecular Function: 3',5'-cyclic-GMP phosphodiesterase activity [TAS]
    3',5'-cyclic-AMP phosphodiesterase activity [TAS]
    hydrolase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSKYGDNII DFLRYLEKFV KSLTKDNKIE EFKTFDIKSL LYPRNKDYFG NLSKFLLAVI  60
   61 SARIGSNFIN EDDIFEISEL LKEFLGQELE HLPYLSYEEL YVEIVEQVGE INGTVSEIIE 120
  121 AITVTIDFLD TFEKVSQTID RSNEKQKLLA YLSAPVNQLD NSVSGVFNEN DYTDIQRFFT 180
  181 ELTNENNQSP DSNISILIND FQSLLNILES QQASSSSSKM IINDSPRTQQ RNGTTEQQKK 240
  241 QQQQQYLQKN KEPFYSKDKI MQVSGPSYVF TPSDCNVSIQ VGIPPDTLKR DQSICHFIVP 300
  301 HFLISKDVSL SEVEFPIFYN KFVQKGKTKV VIICTVEQKQ RIETILCESI FGPAPEHIYT 360
  361 DEEITIPDYK IDLLTERLAI DPRANDEKLD SYVIFKTFDT FGVVDIDLPS ASDPTKLINL 420
  421 RIRNTKGLIS FHEDYHVVQK QLHLKLQEQQ QDQQDKSSSS TTDKQMINTS GNRIILKNNT 480
  481 VSVIDSTIES QYVPVLPFGN DHEQVKKFKA PILGVTFLGV SHGLDFTHCS HTTGFIIWIN 540
  541 GSGVVVDPPV GNTTYLQTNG IYGKTVEHII LTHCHADHDS GILQKIIERN KVTLYTTKTI 600
  601 NESYMRKLKA LTGLPEQSLK NYYTWVPVTI GNKIKILGAE FEFDYSFHVI PTIRFKLEIY 660
  661 NKKISYSADT FYDLQKFKQL KDQGVLSKKR IERLKSFVFD ADMIIHESGV APIHTPMANL 720
  721 LELPSEIRKK IRVVHCSSSV DTKGEIIRPK EGLENTEIIK VDRKYKGVAE CIQIQTALNH 780
  781 CSVFSKLSPA EVQRVFFLCK KIWVKRNDVI IKKGSPSDMF YIILSGKVLV YENEYEPIKS 840
  841 TTSVGTVVTD TTTITTTVKT DAIKIPTIKL CAGETLGESA LQLDKNIDAS ATVIAETDVC 900
  901 LLVWKTMDLR TEFHSNLNTF ISKVHMDLSH INSCRDAIIR AFQHNITQHI NKEEVDSIAN 960
  961 GSKDVSFAHH QVIFNEGDTS DSMYIIKQGR VRIHSKKNKN IIRYLNVGDF FGETAYRRSN1020
 1021 EDSNFLPTRS FTATAIDPTI LLKLDIESIV NPRIQNIIEQ KAKKNAEDNI RYHAYSPKIR1080
 1081 TPRTPRKVYP IEGLSI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle