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Protein Overview: PPCS1_ARATH

General Information:
Name(s) found: PPCS1_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|30682728|ref|NP_563904.2| ATCOAB (4-phospho-panto-thenoylcysteine synthetase); catalytic/ phosphopantothenate--cysteine ligase [Arabidopsis thaliana] [NCBI NR]
  • gi|26451224|dbj|BAC42714.1| unknown protein [Arabidopsis thaliana] [NCBI NR]
  • Phosphopantothenate--cysteine ligase 1 OS=Arabidopsis thaliana GN=PPCS1 PE=2 SV=1 [Swiss-Prot]
  • unknown protein [Arabidopsis thaliana]gi|30682728|ref|NP_563904.2| DNA/panthothenate metabolism flavoprotein family protein [Arabidopsis thaliana] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 DNA/panthothenate metabolism flavoprotein family protein [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: ATCOAB | ATCOAB (4-PHOSPHO-PANTO-THENOYLCYSTEINE SYNTHETASE); catalytic/ phosphopantothenate--cysteine ligase | chr1:4198868-4200631 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • unknown protein [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • catalytic [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: ATCOAB, COAB | 4-phospho-panto-thenoylcysteine synthetase | chr1:4198870-4200633 FORWARD LENGTH=317 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 317 amino acids

    Gene Ontology:
    Cellular Component: chloroplast [IEA]
    Biological Process: coenzyme A biosynthetic process [IDA]
    Molecular Function: catalytic activity [ISS]
    phosphopantothenate--cysteine ligase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSISGLVED EISSFFESSP PLKNKEEIVA NLNQFIELNS SCQGGMRRIV CVTSGGTTVP  60
   61 LEQRCVRYID NFSSGNRGAA STENFVKAGY AVIFLYRRGT CQPYCRYLPD DPFLECFEFP 120
  121 DAKNIQVHGS HSGAVKMAVM DQQAAVAEGR LLKLPFSTIY EYLQMLRLIA TILKDVGPCS 180
  181 MFYLAAAVSD FYVPWLSMTE HKIESGSGPL DIRLAQVPKM LSILRSNWAP KAFCISFKLE 240
  241 TDSKILLEKA TKALQKYKVH AVVANELLTR KEEVVVVSSS GNVVVRRDSN KPESIVEDNL 300
  301 IRLLVDRHST YIKESLT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..317] PSI-BLAST 71.69897 Crystal Structure of Phosphopantothenoylcysteine Synthetase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphopantothenate--cysteine ligase activity
    		•  5.69075768451173 bayes_pls_golite062009
  • phosphopantothenoylcysteine decarboxylase activity
    		•  5.47152792211468 bayes_pls_golite062009
  • ligase activity
    		•  2.22669253992824 bayes_pls_golite062009
  • binding
    		•  1.89072001556053 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  1.60765845284251 bayes_pls_golite062009
  • catalytic activity
    		•  1.32370671504792 bayes_pls_golite062009
  • carboxy-lyase activity
    		•  1.28899846789805 bayes_pls_golite062009
  • carbon-carbon lyase activity
    		•  0.53776941010038 bayes_pls_golite062009
  • protein binding
    		•  0.395135807048731 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.133284065682966 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle