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Protein Overview: LCBK1_ARATH

General Information:
Name(s) found: LCBK1_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|9695279|dbj|BAB07787.1| sphingosine kinase [Arabidopsis thaliana] [NCBI NR]
  • gi|75180325|sp|Q9LRB0.1|LCBK1_ARATH RecName: Full=Sphingoid long-chain bases kinase 1; Short=LCB kinase 1; Short=AtLCBK1; AltName: Full=Sphingosine kinase 1 [NCBI NR]
  • gi|30688996|ref|NP_851065.1| ATLCBK1 (A. THALIANA LONG-CHAIN BASE (LCB) KINASE 1); D-erythro-sphingosine kinase/ diacylglycerol kinase [Arabidopsis thaliana] [NCBI NR]
  • gi|28416519|gb|AAO42790.1| AT5g23450/K19M13_8 [Arabidopsis thaliana] [NCBI NR]
  • gi|22654975|gb|AAM98080.1| AT5g23450/K19M13_8 [Arabidopsis thaliana] [NCBI NR]
  • gi|18420680|ref|NP_568432.1| ATLCBK1 (A. THALIANA LONG-CHAIN BASE (LCB) KINASE 1); D-erythro-sphingosine kinase/ diacylglycerol kinase [Arabidopsis thaliana] [NCBI NR]
  • Sphingoid long-chain bases kinase 1 OS=Arabidopsis thaliana GN=LCBK1 PE=1 SV=1 [Swiss-Prot]
  • AT5g23450/K19M13_8 [Arabidopsis thaliana]gi|28416519|gb|AAO42790.1| AT5g23450/K19M13_8 [Arabidopsis thaliana]gi|30688996|ref|NP_851065.1| diacylglycerol kinase family protein [Arabidopsis thaliana]gi|18420680|ref|NP_568432.1| diacylglycerol kinase fami [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Diacylglycerol kinase family protein [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: ATLCBK1 | ATLCBK1 (A. THALIANA LONG-CHAIN BASE (LCB) KINASE 1); diacylglycerol kinase | chr5:7905044-7908963 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • AT5g23450/K19M13_8 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • ATLCBK1 (A. THALIANA LONG-CHAIN BASE (LCB) KINASE 1); diacylglycerol kinase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • sphingosine kinase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: ATLCBK1, LCBK1 | long-chain base (LCB) kinase 1 | chr5:7905041-7908960 REVERSE LENGTH=763 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 763 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [IDA]
    Biological Process: activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway [ISS]
    sphingolipid biosynthetic process [IDA]
    Molecular Function: D-erythro-sphingosine kinase activity [IDA]
    diacylglycerol kinase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQKSGVNRNP SLKVAIPQAQ QSLRRLGFCS QIATGGSQQS SPIVFPEKRN KKVKASSRRG  60
   61 EVTNDPQVKP KPDEHRIDIG GGDEKSDLLG SLVYAGKLVL DKRKSASGKD ATEIQQPAAT 120
  121 DISIKKAVDA KLTSSALVWG SDMLQLNDVV SVTYNVGLRH FTVHAYPIGK GSCGLSCFTK 180
  181 PKRSRKDFRF VAPTVEEAVQ WVASFGDQQC FINCLPHPLV AKKQASSELF SVPIDTPPEL 240
  241 VFRCKSAPKM LVILNPRSGH GRSIKVFHNV VEPIFKLAGI KMEVVKTTKA GHARELASTV 300
  301 DINLCSDGII CVGGDGIINE VLNGLLTRSN PKEGVSIPIG IVPAGSDNSL VWTVLGVRDP 360
  361 ISAALSIVKG GLTATDVFAV EWIHTGIIHF GMTVSYYGFV SDVLELSEKY QKRFGPLRYF 420
  421 VAGFLKFMCL PKYSYEVEYL PAQKEDAEGK IRLEKEAVDM QDLYTDVMRR SSREGFPRAS 480
  481 SLSSIDSIMT PSVGELDTCS STHASTEPSE YVRGIDPKMK RLSSGRRDVT AEPEVIHPQA 540
  541 QSTTPNWPRT RSKSRMDKGW MGLTSVQDPP TRCSWGNTGG QDREDISSTV SDPGPIWDAG 600
  601 PKWDTEPSAW DVENSIELPG PPEDIETGLR KQSITPIFED KWVSRKGHFL GIMVCNHACR 660
  661 TVQSSQVVAP NSEHDDGTMD MLLVHGCGRL RLLRFFILLQ TGRHLSLPYV ECVKVKSVKI 720
  721 KAGKNTHDSC GIDGELFALH GEVISTMLPE QCRLIGNAPG RHS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..117] deduced N/A No confident structure predictions are available.
    2 View Details [118..246] PSI-BLAST 11.0 Solution Structure of The C1 Domain of The Human Diacylglycerol Kinase Delta
    3 View Details [247..557] PSI-BLAST 41.0 No description for 2jgrA was found.
    4 View Details [558..763] FFAS03 3.07 No description for 2bonA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle