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Protein Overview: plexA-PE

General Information:
Name(s) found: plexA-PE / FBpp0099691 [FlyBase]
Description(s) found:
Found 12 descriptions.
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  • The gene plexin A is referred to in FlyBase by the symbol Dmel\plexA (CG11081, FBgn0025741). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 4:1034030..1047720. It has the cytological map location 102F5-102F6. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: axon guidance; axon midline choice point recognition. 10 alleles are reported. The phenotypes of these alleles are annotated with: ventral nerve cord; intersegmental nerve; longitudinal connective; embryonic central nervous system; abdominal segmental nerve; abdominal intersegmental nerve; transverse nerve. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 419 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    intracellular [IEA]
    Biological Process: motor axon guidance [NAS]
    signal transduction [IEA]
    axon guidance [IMP]
    axon midline choice point recognition [IMP]
    Molecular Function: protein binding [IPI]
    semaphorin receptor activity [ISS][TAS]
    axon guidance receptor activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNFVLSVLLI AILKDKYDYW LPSRTGCQTL AANIWSDKTT AQNEPINLTN ANAPIKNAKN  60
   61 LNSTITNVAA FDTKLNHLLV DTITGRVFVG GVNRLYQLSP DLELSETVKT GPQNDSVECS 120
  121 ILDCPLNAVR SPTDNYNKVL LIDRATSRLI ACGSLFQGTC TVRNLQNVSI IEHEVPDAVV 180
  181 ANDANSSTVA FIAPGPPQHP VTNVMYVGVT YTNNSPYRSE IPAVASRSLE KTKMFQIASS 240
  241 AVTTGTRTFI NSYARETYFV NYVYGFSSER FSYFLTTQLK HSHHSSPKEY ITKLVRICQE 300
  301 DSNYYSYTEI PVECISDAQG GTKFNLVQAG FLGKPSSDLA QSLGISIQDD VLFAVFSKGE 360
  361 GNTPTNNSAL CIYSLKSIRR KFMQNIKSCF NGSGMRGLDF ISPSMPCVLT SGEQALLGE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..419] PSI-BLAST 64.0 No description for 2uzxB was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle