YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: mre-11

General Information:
Name(s) found: mre-11 / CE37459 [WormBase]
Description(s) found:
Found 16 descriptions.
SHOW ALL
  • WBGene00003405 locus:mre-11 Double-strand break repair protein mre-11 status:Partially_confirmed UniProt:Q23255 protein_id:CAA98292.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 728 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    germline cell cycle switching, mitotic to meiotic cell cycle [IMPLink to PubMed article]
    chromosome segregation [IMPLink to PubMed article]
    DNA metabolic process [IEALink to PubMed article]
    double-strand break repair [IEALink to PubMed article]
    Molecular Function: exonuclease activity [IEALink to PubMed article]
    endonuclease activity [IEALink to PubMed article]
    manganese ion binding [IEALink to PubMed article]
    hydrolase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCGSDDSFDD FVPDSQEPAS SRTRNQDHLD DDEVPCSQRP DAANDTMVED LDEGDEPAHD  60
   61 ESEDIIKILV ATDIHCGYGE NKANIHMDAV NTFEEVLQIA TEQKVDMILL GGDLFHENNP 120
  121 SREVQHRVTQ LLRQYCLNGN PIALEFLSDA SVNFNQSVFG HVNYYDQNLN VGLPIFTIHG 180
  181 NHDDLSGKGL TALDLLHESG LVNLFGKHSN IQEFIVSPIL LRKGETRLAL YGIGSQRDDR 240
  241 LVRAFKNNSI SFLRPNAGAE DWFNLFVLHQ NRPRRAMHRS TGNFLPESLI PQFFDLLIWG 300
  301 HEHECKPDPQ YVASSEAVGD GFYILQPGST VATSLTPEEA LQKNAFLIKI KGRKFASKPI 360
  361 PLQTVRPMVC DELLLDKIPP GSRPILKTDR PKHTDGRYID EIAIEAKINE MITTAKAKRR 420
  421 PRQPELPLIR LKVIYDGDWL NITPANAKRI GLRYENVVAN AVDMVFIKKN NKPKEGKLQT 480
  481 ENEKNITEMA DEMGQVSATN LQTIINDYFI NQPLVDQMTV LKPIGIGRAL EQYSAIEEGG 540
  541 LATSANRNFD SCLMHQIDVV RKTLKKMPLP PINDPSDLDK FRDLITKDLY DMKKADSERF 600
  601 KNPVADVEME EDEDDPQYYM PPQSTSRTNY ASGSEDEVAN SDEEMGSSIS RHSKQPTTRG 660
  661 RGRGARGAGA SRETTRGRSN KVVSTRQIDS DGFEIINDSP SPPPASRSTR GKARGKSAPS 720
  721 KKRDLSFF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..456] PSI-BLAST 45.39794 Mre11
    2 View Details [457..535] deduced N/A No confident structure predictions are available.
    3 View Details [536..728] MSA 7.098997 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphoprotein phosphatase activity
    		•  1.43500260769599 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  1.24384090418481 bayes_pls_golite062009
  • protein serine/threonine phosphatase activity
    		•  1.243831086941 bayes_pls_golite062009
  • phosphatase activity
    		•  1.22221319991731 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.685850975270683 bayes_pls_golite062009
  • hydrolase activity
    		•  0.135444325609812 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle