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Protein Overview: DYHC_DICDI

General Information:
Name(s) found: DYHC_DICDI [Swiss-Prot]
Description(s) found:
Found 6 descriptions.
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  • Dynein heavy chain, cytoplasmic OS=Dictyostelium discoideum GN=dhcA PE=1 SV=2 [Swiss-Prot]
    • Organism: Dictyostelium discoideum
    Length: 4730 amino acids

    Gene Ontology:
    Cellular Component: endocytic vesicle [IDA]
    centrosome [IDA][TAS]
    cytoplasmic dynein complex [IDA]
    cytoplasm [IDA]
    cell cortex [IDA]
    microtubule [IPI]
    Biological Process: cytoplasmic microtubule organization [IMP]
    microtubule-based movement [IEA]
    Molecular Function: ATPase activity [IDA]
    ATP binding [IDA]
    tubulin binding [IDA][IPI]
    microtubule motor activity [IEA]
    protein binding [IPI]
    ATPase activity, coupled [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDQQINVDS PTSGTNTPPV VTPTTSVISE QTLEETVKYL CKICPTLLDG DQSVFQNNLS  60
   61 NQIPPENMNK LKKFISDSKI PVLLIQKTNP TINSSNQTST TTSSSSSSDD NTLTSSQQQS 120
  121 KESFNFEIEV KFGGENKSTL AIVKRIPESI VEYSSNKSIA SQLQVLNLGD GSPMDTLHNY 180
  181 IHNSVAPFVR SYILSASKDD ATTPSGGSAD KSITSQNLDK EMKQSIGAVN QKIAELEISL 240
  241 YNCKQQVQIP EVTLAINPEI KSISKRLKET TGRTIKPDDL GDKASSPEFL NLLQAGTTTW 300
  301 AKNIQNVTKH NLIENLPSDV STSQEINFWI ELETSLQNID QQLKSPEVEV TLATLRQAKR 360
  361 FIASAPFETD TIGVRKAMDK VQSYKTLFKD FPITPLLTAT DLDSISSSVA AIFSHLKKTK 420
  421 NPYYPIPRYL SFLEAIGRDM CNKVYQILRQ KNLMNIDYND FEHLNRSVRA LFTLWDDQFG 480
  481 AFRDILRDLA KKRGNERIPL IVNIDNRIQL VIIKIGKFRK QHEDLKNVVS NVLPGSQLGG 540
  541 GVVQTNTSNP TSPQKQEINA IEEINQAYLE FKEIDVLQLS KEGEEIWDAV VKRYNSRTDR 600
  601 VETYITVKLR DRLATAKNAN EMFRVYQKFK DLLKRPKIRG ATHEYESQLI ERVKEDIRVL 660
  661 HDKFKMQYNN SEAYYMSQLR DLPPVSGAII WARQIERQLD TYMKRVANVL GDSWESDAEG 720
  721 QKLKSESDQF RHKLNTDHIF SKWADETEKR SFDISGRILT IVKRGNKLAL DINFDSHIIM 780
  781 LFKEVRNLQW LGFRVPLKIS FISQGAKQVY PFAVSLKETL RTYAQTSGKV TPEFSTLVAS 840
  841 YKRDVQANIT EGFRLKWETI PKVDPYVRKL STSINNFRDK VDDLIVKYSE IKKQLDGLKS 900
  901 CPFKSESFNE IIANIQKVVD ELNLANYSNL PQWVTQLDAQ VESMLIERLI DAINSWVQLI 960
  961 EGKEDQKDSQ STSGSSNKGG KLNRMNYSIR NKSDEENSSD LTQPQQSQQQ QQTISIKPKL1020
 1021 EKTIHEIVIR NQILSLSPPL EVARVNWIDQ LHSWLNICCD LPRIQSSRYD ESAMVHRGGV1080
 1081 DSKKQSTFRD MLPKLPQGSL ESAYSAITNK LEQVQQYVSI WLQYQSLWDM DSSFVYSKLG1140
 1141 DDLNKWQLLL NQIKKSRSTF DNSSTEKQFG PLTIDYTQVQ ASVNNKYDYW HKDILGHFGS1200
 1201 KLAEKMNQFY ETISSSRQEL EKLSVETVST EEAVHFIIQI QDMKKKLSSW EADLRYYRTG1260
 1261 QDLLQRQRFS FPNDWLDCER VEGEWSAFNE ILNRKNATIS EAIPQLQAKI LQESKSINDR1320
 1321 IKDFIDEWTA NKPLQGSIKH STALETLKIF EGRLIRLREE SDRLSKAKQA LDLTDTTGSS1380
 1381 SSDQDRLVPV EEEIQDLKAV WVELSNTWQE IDSLKETAWS AIIPRKVRKS LEDTLQKLKN1440
 1441 LPNRIRQYSA FDHAQNLIKI YLKGNAIITD LHSEAIKDRH WKILKKRLNT NWIITELTLG1500
 1501 SIWDSDLARN ENIYREVITA AQGEIALEEF LKGVREFWTT LELDLVNYQR KCKLVRGWDD1560
 1561 LFNKLAEHLN SISAMKMSPY YKVFEEEANH WDDRLNKVRS LLDVWIDVQR RWVYLEGIFS1620
 1621 GSGDINQLLP AESTRFKSIN SEFIAILKKV SGAPLILEVL AIERIQQTME RLSDLLGKVQ1680
 1681 KALGEYLERQ RSAFARFYFV GDEDLLEIIG NSKDIIKIQK HFRKMFAGLA NLTLDDEKTT1740
 1741 IIGMSSAEGE TVTFKKPISI ANGPKIHEWL TMVESEMKST LATLLSESLQ HFNQVDVNDH1800
 1801 SKYSEWVDNY PTQLVLLTSQ IVWSTQVDQA LGGGTLQQSK IQEQLQSIEQ TTQMILNNLA1860
 1861 DSVLQDLSAQ KRKKFEHLIT ELVHQRDVVR QLQKCKNLTG NKDFDWLYHM RYYYDATQEN1920
 1921 VLHKLVIHMA NATFYYGFEY LGIGERLVQT PLTDRCYLTL TQALESRMGG NPFGPAGTGK1980
 1981 TETVKALGSQ LGRFVLVFCC DEGFDLQAMS RIFVGLCQCG AWGCFDEFNR LEERILSAVS2040
 2041 QQIQTIQVAL KENSKEVELL GGKNISLHQD MGIFVTMNPG YAGRSNLPDN LKKLFRSMAM2100
 2101 IKPDREMIAQ VMLYSQGFKT AEVLAGKIVP LFKLCQEQLS AQSHYDFGLR ALKSVLVSAG2160
 2161 GIKRKCQPPQ LPPITDAESK TKADQIYCQY EIGVLLNSIN DTMIPKLVAD DIPLIQSLLL2220
 2221 DVFPGSQLQP IQMDQLRKKI QEIAKQRHLV TKQEWVEKIL QLHQILNINH GVMMVGPSGG2280
 2281 GKTTSWEVYL EAIEQVDNIK SEAHVMDPKA ITKDQLFGSL DLTTREWTDG LFTATLRRII2340
 2341 DNVRGESTKR HWIIFDGDVD PEWVENLNSL LDDNKLLTLP NGERLALPNN VRVMFEVQDL2400
 2401 KYATLATISR CGMVWFSEEI LTTQMIFQNY LDTLSNEPFD PQEKEQQKRN ENAQLQQQQQ2460
 2461 TTITSPILTS PPTTSSSSRS TTSTTSMIPA GLKVQKECAA IISQYFEPGG LVHKVLEDAG2520
 2521 QRPHIMDFTR LRVLNSFFSL MNRSIVNVIE YNQLHSDFPM SPENQSNYIT NRLLYSLMWG2580
 2581 LGGSMGLVER ENFSKFIQTI AITPVPANTI PLLDYSVSID DANWSLWKNK VPSVEVETHK2640
 2641 VASPDVVIPT VDTTRHVDVL HAWLSEHRPL ILCGPPGSGK TMTLTSTLRA FPDFEVVSLN2700
 2701 FSSATTPELL LKTFDHHCEY KRTPSGETVL RPTQLGKWLV VFCDEINLPS TDKYGTQRVI2760
 2761 TFIRQMVEKG GFWRTSDHTW IKLDKIQFVG ACNPPTDAGR VQLTHRFLRH APILLVDFPS2820
 2821 TSSLTQIYGT FNRALMKLLP NLRSFADNLT DAMVEFYSES QKRFTPDIQA HYIYSPRELS2880
 2881 RWDRALLEAI QTMDGCTLEG LVRLWAHEAL RLFQDRLVET EEKEWTDKKI DEVALKHFPS2940
 2941 VNLDALKRPI LYSNWLTKDY QPVNRSDLRE YVKARLKVFY EEELDVPLVL FNEVLDHILR3000
 3001 IDRVFRQPQG HALLIGVSGG GKSVLSRFVA WMNGLSIYTI KVNNNYKSSD FDDDLRMLLK3060
 3061 RAGCKEEKIC FIFDESNVLE SSFLERMNTL LAGGEVPGLF EGEEFTALMH ACKETAQRNG3120
 3121 LILDSEEELY KYFTSQVRRN LHVVFTMNPA SPDFHNRSAT SPALFNRCVL DWFGEWSPEA3180
 3181 LFQVGSEFTR NLDLENPQYI APPVFIQEAE IMGNNLMAIP PSHRDAVVSS LVYIHQTIGE3240
 3241 ANIRLLKRQG RQNYVTPRHY LDFINQVVLL INEKRDQLEE EQLHLNIGLK KLRDTEAQVK3300
 3301 DLQVSLAQKN RELDVKNEQA NQKLKQMVQD QQAAEIKQKD ARELQVQLDV RNKEIAVQKV3360
 3361 KAYADLEKAE PAIIEAQEAV STIKKKHLDE IKSLPKPPTP VKLAMEAVCL MLGGKKLEWA3420
 3421 DIRKKIMEPN FITSIINYDT KKMMTPKIRE AITKGYLEDP GFDYETVNRA SKACGPLVKW3480
 3481 ATAQTYYSEI LDRIKPLREE VEQLENAANE LKLKQDEIVA TITALEKSIA TYKEEYATLI3540
 3541 RETEQIKTES SKVKNKVDRS IALLDNLNSE RGRWEQQSEN FNTQMSTVVG DVVLASAFLA3600
 3601 YIGFFDQNFR TDLMRKWMIR LDSVGIKFKS DLSVPSFLSK PEERLNWHAN SLPSDELCIE3660
 3661 NAIMLKRFNR YPLVIDPSGQ AMEFLMNQYA DKKITKTSFL DSSFMKNLES ALRFGCPLLV3720
 3721 QDVENIDPVL NPVLNKEIRK KGGRILIRLG DQDVDFSPSF MIFLFTRDPT AHFTPDLCSR3780
 3781 VTFVNFTVTP SSLQSQCLHE ALKTERPDTH KKRSDLLKIQ GEFQVKLRIL EKSLLNALSQ3840
 3841 ASGNILDDDS VISTLETLKK ETTEIALKVE ETETVMQEIS EVSALYNPMA LSCSRVYFAM3900
 3901 EELSQFHLYQ FSLRAFLDIF YNLLNNNPNL VDKKDPNERL VYLSKDIFSM TFNRVTRTLL3960
 3961 NDDKLTFALQ LTIISVKGTS NEIEESEWDF LLKGGDNLTS IKETIPQLDS LLSTTQQKWL4020
 4021 ICLRQQVPSF SKLVDHIQQN SSDWKQFFGK DQVGEPIIPE SWIVAQAQLS NQQSTIVSNF4080
 4081 RKILLMKAFH SDRVLQYSHS FVCSVFGEDF LNTQELDMAN IVEKEVKSSS PLLLCSVPGY4140
 4141 DASSKVDDLA LQLHKQYKSF AIGSPEGFEL AEKSIYAAAK SGTWVLLKNI HLAPQWLVQL4200
 4201 EKKLHSLSPH PSFRLFMTSE IHPALPANLL RMSNVFSYEN PPGVKANLLH TFIGIPATRM4260
 4261 DKQPAERSRI YFLLAWFHAI IQERLRYIPL GWTKFFEFND ADLRGALDSI DYWVDLYSKG4320
 4321 RSNIDPDKIP WIAVRTILGS TIYGGRIDNE FDMRLLYSFL EQLFTPSAFN PDFPLVPSIG4380
 4381 LSVPEGTTRA HFMKWIEALP EISTPIWLGL PENAESLLLS NKARKMINDL QKMQSSEEDG4440
 4441 EDDQVSGSSK KESSSSSSED KGKAKLRATI TEWTKLLPKP LKQLKRTTQN IKDPLFRCFE4500
 4501 REISTGGKLV KKITNDLANL LELISGNIKS TNYLRSLTTS ISKGIVPKEW KWYSVPETIS4560
 4561 LSVWISDFSK RMQQLSEISE SSDYSSIQVW LGGLLNPEAY ITATRQSASQ LNGWSLENLR4620
 4621 LHASSLGKIS SEGGASFNVK GMALEGAVWN NDQLTPTDIL STPISIATLT WKDKDDPIFN4680
 4681 NSSSKLSVPV YLNETRSELL FSIDLPYDQS TSKQNWYQRS VSISSWKSDI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle