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Protein Overview: Dcp2-PB, Dcp2-PD

General Information:
Name(s) found: Dcp2-PD / FBpp0099969 [FlyBase]
Dcp2-PB / FBpp0075294 [FlyBase]
Description(s) found:
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  • gi|62484460|ref|NP_730074.2| decapping protein 2, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|62472192|ref|NP_001014585.1| decapping protein 2, isoform D [Drosophila melanogaster] [NCBI NR]
  • gi|61678461|gb|AAX52744.1| decapping protein 2, isoform D [Drosophila melanogaster] [NCBI NR]
  • gi|61678460|gb|AAN11769.2| decapping protein 2, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|28557559|gb|AAO45185.1| SD14939p [Drosophila melanogaster] [NCBI NR]
  • The gene Decapping protein 2 is referred to in FlyBase by the symbol Dmel\Dcp2 (CG6169, FBgn0036534). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:15814087..15819519. It has the cytological map location 72A1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: RNA binding; hydrolase activity; manganese ion binding. There is experimental evidence that it is involved in the biological process</span>: nuclear-transcribed mRNA catabolic process; gene silencing by miRNA. 7 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
  • SD14939p [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3L:complement(15814545..15815111,15815171..15815908,15816063..15816281,15816347..15816517); ID=FBpp0075294; name=Dcp2-PB; parent=FBgn0036534,FBtr0075539; dbxref=GB_protein:AAN11769.1,FlyBase_Annotation_IDs:CG6169-PB,FlyBase:FBpp0075294,G [fly-100309-contam.fasta]
  • type=protein; loc=3L:complement(15814545..15815111,15815171..15815908,15816063..15816281,15816347..15816517); ID=FBpp0099969; name=Dcp2-PD; parent=FBgn0036534,FBtr0100528; dbxref=FlyBase_Annotation_IDs:CG6169-PD,FlyBase:FBpp0099969,GB_protein:AAX52744.1,R [fly-100309-contam.fasta]
  • CG6169-PD, isoform D [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG6169-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3L:complement(15814545..15815111,15815171..15815908,15816063..15816281,15816347..15816517); ID=FBpp0075294; name=Dcp2-PB; parent=FBgn0036534,FBtr0075539; dbxref=GB_protein:AAN11769.1,FlyBase_Annotation_IDs:CG6169-PB,FlyBase:FBpp0075294,GB_protein:AAN11769.2,REFSEQ:NP_730074,GB_protein:AAN11769; MD5=1c1a456b49a7464ffc52e0389d13cfa9; length=564; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3L:complement(15814545..15815111,15815171..15815908,15816063..15816281,15816347..15816517); ID=FBpp0099969; name=Dcp2-PD; parent=FBgn0036534,FBtr0100528; dbxref=FlyBase_Annotation_IDs:CG6169-PD,FlyBase:FBpp0099969,GB_protein:AAX52744.1,REFSEQ:NP_001014585,GB_protein:AAX52744; MD5=1c1a456b49a7464ffc52e0389d13cfa9; length=564; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3L:complement(15814545..15815111,15815171..15815908,15816063..15816281,15816347..15816517); ID=FBpp0075294; name=Dcp2-PB; parent=FBgn0036534,FBtr0075539; dbxref=GB_protein:AAN11769.1,FlyBase_Annotation_IDs:CG6169-PB,FlyBase:FBpp0075294,GB_protein:AAN11769.2,REFSEQ:NP_730074,GB_protein:AAN11769; MD5=1c1a456b49a7464ffc52e0389d13cfa9; length=564; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=3L:complement(15814545..15815111,15815171..15815908,15816063..15816281,15816347..15816517); ID=FBpp0099969; name=Dcp2-PD; parent=FBgn0036534,FBtr0100528; dbxref=FlyBase_Annotation_IDs:CG6169-PD,FlyBase:FBpp0099969,GB_protein:AAX52744.1,REFSEQ:NP_001014585,GB_protein:AAX52744; MD5=1c1a456b49a7464ffc52e0389d13cfa9; length=564; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Decapping protein 2, isoform B OS=Drosophila melanogaster GN=Dcp2 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3L:complement(15814545..15815111,15815171..15815908,15816063..15816281,15816347..15816517); ID=FBpp0075294; name=Dcp2-PB; parent=FBgn0036534,FBtr0075539; dbxref=GB_protein:AAN11769.1,FlyBase_Annotation_IDs:CG6169-PB,FlyBase:FBpp0075294,GB_protein:AAN11769.2,REFSEQ:NP_730074,GB_protein:AAN11769,FlyMine:FBpp0075294,modMine:FBpp0075294; MD5=1c1a456b49a7464ffc52e0389d13cfa9; length=564; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3L:complement(15814545..15815111,15815171..15815908,15816063..15816281,15816347..15816517); ID=FBpp0099969; name=Dcp2-PD; parent=FBgn0036534,FBtr0100528; dbxref=FlyBase_Annotation_IDs:CG6169-PD,FlyBase:FBpp0099969,GB_protein:AAX52744.1,REFSEQ:NP_001014585,GB_protein:AAX52744; MD5=1c1a456b49a7464ffc52e0389d13cfa9; length=564; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3L:complement(join(15823247..15823417,15822963..15823181,15822071..15822808,15821445..15822011)); ID=FBpp0075294; name=DCP2-PB; parent=FBgn0036534,FBtr0075539; dbxref=GB_protein:AAN11769.1,FlyBase_Annotation_IDs:CG6169-PB,FlyBase:FBpp0075294,GB_protein:AAN11769.2,REFSEQ:NP_730074,GB_protein:AAN11769,FlyMine:FBpp0075294,modMine:FBpp0075294; MD5=1c1a456b49a7464ffc52e0389d13cfa9; length=564; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:complement(join(15823247..15823417,15822963..15823181,15822071..15822808,15821445..15822011)); ID=FBpp0099969; name=DCP2-PD; parent=FBgn0036534,FBtr0100528; dbxref=FlyBase_Annotation_IDs:CG6169-PD,FlyBase:FBpp0099969,GB_protein:AAX52744.1,REFSEQ:NP_001014585,GB_protein:AAX52744; MD5=1c1a456b49a7464ffc52e0389d13cfa9; length=564; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:complement(join(15823247..15823417,15822963..15823181,15822071..15822808,15821445..15822011)); ID=FBpp0075294; name=DCP2-PB; parent=FBgn0036534,FBtr0075539; dbxref=GB_protein:AAN11769.1,FlyBase_Annotation_IDs:CG6169-PB,FlyBase:FBpp0075294,GB_protein:AAN11769.2,REFSEQ:NP_730074,GB_protein:AAN11769,FlyMine:FBpp0075294,modMine:FBpp0075294; MD5=1c1a456b49a7464ffc52e0389d13cfa9; length=564; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=3L:complement(join(15823247..15823417,15822963..15823181,15822071..15822808,15821445..15822011)); ID=FBpp0099969; name=DCP2-PD; parent=FBgn0036534,FBtr0100528; dbxref=FlyBase_Annotation_IDs:CG6169-PD,FlyBase:FBpp0099969,GB_protein:AAX52744.1,REFSEQ:NP_001014585,GB_protein:AAX52744; MD5=1c1a456b49a7464ffc52e0389d13cfa9; length=564; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of Q5U127, Decapping protein 2, isoform B OS=Drosophila melanogaster GN=DCP2 PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0075294 type=protein; loc=3L:complement(join(15823247..15823417,15822963..15823181,15822071..15822808,15821445..15822011)); ID=FBpp0075294; name=DCP2-PB; parent=FBgn0036534,FBtr0075539; dbxref=GB_protein:AAN11769.1,FlyBase_Annotation_IDs:CG6169-PB,FlyBase:FBpp0075294,GB_protein:AAN11769.2,REFSEQ:NP_730074,GB_protein:AAN11769,FlyMine:FBpp0075294,modMine:FBpp0075294; MD5=1c1a456b49a7464ffc52e0389d13cfa9; length=564; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0099969 type=protein; loc=3L:complement(join(15823247..15823417,15822963..15823181,15822071..15822808,15821445..15822011)); ID=FBpp0099969; name=DCP2-PD; parent=FBgn0036534,FBtr0100528; dbxref=FlyBase_Annotation_IDs:CG6169-PD,FlyBase:FBpp0099969,GB_protein:AAX52744.1,REFSEQ:NP_001014585,GB_protein:AAX52744; MD5=1c1a456b49a7464ffc52e0389d13cfa9; length=564; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3L:complement(join(15823247..15823417,15822963..15823181,15822071..15822808,15821445..15822011)); ID=FBpp0075294; name=DCP2-PB; parent=FBgn0036534,FBtr0075539; dbxref=GB_protein:AAN11769.1,FlyBase_Annotation_IDs:CG6169-PB,FlyBase:FBpp0075294,GB_protein:AAN11769.2,REFSEQ:NP_730074,GB_protein:AAN11769,UniProt/TrEMBL:Q86NM7,FlyMine:FBpp0075294,modMine:FBpp0075294; MD5=1c1a456b49a7464ffc52e0389d13cfa9; length=564; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=3L:complement(join(15823247..15823417,15822963..15823181,15822071..15822808,15821445..15822011)); ID=FBpp0099969; name=DCP2-PD; parent=FBgn0036534,FBtr0100528; dbxref=FlyBase_Annotation_IDs:CG6169-PD,FlyBase:FBpp0099969,GB_protein:AAX52744.1,REFSEQ:NP_001014585,GB_protein:AAX52744,UniProt/TrEMBL:Q86NM7; MD5=1c1a456b49a7464ffc52e0389d13cfa9; length=564; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 564 amino acids

    Gene Ontology:
    Cellular Component: cytoplasmic mRNA processing body [IDA]
    Biological Process: [NOT]nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [IMP]
    gene silencing by miRNA [IMP]
    nuclear-transcribed mRNA catabolic process [IMP]
    Molecular Function: RNA binding [IEA]
    manganese ion binding [IEA]
    hydrolase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELNNLIRMC FQIELAHWFY LDFFCAPESG EDGETPKCVQ RKLPSVGIKQ FAMQLFQHIP  60
   61 FLNKHFGTVD QILDEWKNYK LSVPTYGAIL VSEDHNHCLL VQSYFARNSW GFPKGKINEN 120
  121 EDPAHCATRE VYEETGFDIT DLIDANDYIE AFINYQYTRL YVVRNIPMDT QFAPRTRNEI 180
  181 KCCDWFRIDA LPVNKNDAIS KAKLGKTSNS FFMIMPFVKR LKKWVNDRKA GIEPRRRKFS 240
  241 GQQSPKAASP TNMNGNCKKD VTGVRNESQR QRHKSMGDLD GVKLNNLNGK GTVGTGAGSA 300
  301 ASASATAAIN SMNICNSNGK RNKQNAAAGS NQATPTTIAT PMTSNGAVVG GTVSSKRQLF 360
  361 HSQSQNDAQQ SASNEKIVSS FDLIRKEKQQ QLKAAKAQKQ QQQQQQRSRT KSQSDKQYNP 420
  421 QQPVKILGQQ QPTTGMDLIA MLSAAAAAQK TPNNEQQTQE KQQQQQRPRP ASVSLNLGAG 480
  481 SATGATTSAP DAQYMHRLQR MASGTNLRIL KRAQSQQPQQ HHQQQLQLEQ QQQQQQQLGI 540
  541 DFTPNLNSWT NFSFTKNFIA NVFC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle