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Protein Overview: AP2A1_ARATH

General Information:
Name(s) found: AP2A1_ARATH [Swiss-Prot]
Description(s) found:
Found 11 descriptions.
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  • AP-2 complex subunit alpha-1 OS=Arabidopsis thaliana GN=ALPHA-ADR PE=1 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 1012 amino acids

    Gene Ontology:
    Cellular Component: membrane [IDA]
    plasma membrane [IDA]
    Biological Process: vesicle-mediated transport [IEA]
    protein transport [IEA]
    intracellular protein transport [IEA]
    Molecular Function: protein binding [IEA]
    protein transporter activity [IEA]
    binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTGMRGLSVF ISDVRNCQNK EAERLRVDKE LGNIRTCFKN EKVLTPYKKK KYVWKMLYIH  60
   61 MLGYDVDFGH MEAVSLISAP KYPEKQVGYI VTSCLLNENH DFLKLAINTV RNDIIGRNET 120
  121 FQCLALTLVG NIGGRDFAES LAPDVQKLLI SSSCRPLVRK KAALCLLRLF RKNPDAVNVD 180
  181 GWADRMAQLL DERDLGVLTS STSLLVALVS NNHEAYSSCL PKCVKILERL ARNQDVPQEY 240
  241 TYYGIPSPWL QVKAMRALQY FPTIEDPSTR KALFEVLQRI LMGTDVVKNV NKNNASHAVL 300
  301 FEALSLVMHL DAEKEMMSQC VALLGKFISV REPNIRYLGL ENMTRMLMVT DVQDIIKKHQ 360
  361 SQIITSLKDP DISIRRRALD LLYGMCDVSN AKDIVEELLQ YLSTAEFSMR EELSLKAAIL 420
  421 AEKFAPDLSW YVDVILQLID KAGDFVSDDI WFRVVQFVTN NEDLQPYAAS KAREYLDKIA 480
  481 IHETMVKVSA YILGEYGHLL ARQPGCSASE LFSILHEKLP TISTPTIPIL LSTYAKLLMH 540
  541 AQPPDPELQK KVWAVFKKYE SCIDVEIQQR AVEYFELSKK GPAFMDVLAE MPKFPERQSS 600
  601 LIKKAENVED TADQSAIKLR AQQQPSNAMV LADQQPVNGA PPPLKVPILS GSTDPESVAR 660
  661 SLSHPNGTLS NIDPQTPSPD LLSDLLGPLA IEAPPGAVSN EQHGPVGAEG VPDEVDGSAI 720
  721 VPVEEQTNTV ELIGNIAERF HALCLKDSGV LYEDPHIQIG IKAEWRGHHG RLVLFMGNKN 780
  781 TSPLTSVQAL ILPPAHLRLD LSPVPDTIPP RAQVQSPLEV MNIRPSRDVA VLDFSYKFGA 840
  841 NVVSAKLRIP ATLNKFLQPL QLTSEEFFPQ WRAISGPPLK LQEVVRGVRP LALPEMANLF 900
  901 NSFHVTICPG LDPNPNNLVA STTFYSESTG AILCLARIET DPADRTQLRM TVGTGDPTLT 960
  961 FELKEFIKEQ LITVPMGSRA LVPAAGPAPP VAQPPSPAAL ADDPGAMLAG LL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..66] FFAS03 1.4 AP1 clathrin adaptor core
    2 View Details [67..655] PSI-BLAST 49.221849 No description for 2iaeA was found.
    3 View Details [656..727] deduced N/A No confident structure predictions are available.
    4 View Details [728..1012] PSI-BLAST 81.69897 Crystal structure of the alpha-adaptin appendage domain, from the AP2 adaptor complex, bound to 2 peptides from Synaptojanin170


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle