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Protein Overview: eps-8

General Information:
Name(s) found: eps-8 / CE39451 [WormBase]
Description(s) found:
Found 14 descriptions.
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  • WBGene00001330 locus:eps-8 status:Confirmed UniProt:G5EFE0 protein_id:CAJ44244.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 740 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    brush border [IDALink to PubMed article]
    Biological Process: locomotory behavior [IMPLink to PubMed articleLink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    growth [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: sequence-specific DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRRGGSMGPP SGDPYQSRPS PGGYYYNRST PGGQPAPSPS HSQQSASSHH PRGVPMSQPI  60
   61 ARRSDYRTGS EQMTPRSDHR GPSMGYGNGG SVDQRVDDVT PSYYVEHLAT FAVGRQFGLT 120
  121 FPADGIRKLK QMEKNSAIWA QPLILRFRHN AVTVEDDNGE LVEQFPLELI EQPTAHVSND 180
  181 SRETYNNVLL FVVREDRKRM STPTEMHIFQ CIRVSATDVA EDLKNYVQGQ FRRVRNGRRT 240
  241 AAPTHLQAQQ QQMPFYPPDD ASISSETSEM FERDVNTLNR CFDDIERFVA RIQSAALAQR 300
  301 EIEQQNHRYR TANRRDKKNQ QPPDPNGILF MRAQLPLESE FVDILKKFKL SFNLLAKLKN 360
  361 HIHEPNAPEL LHFLFTPLAV ILEACHWGLG RNVAPTVASP LLSLEARELM QNCLTSHESD 420
  421 IWMSLGEAWR TPPEDWTKPL PPPYRPIFND GFAPYGVADR AMATPNQIHR GHSAPPEHFR 480
  481 QPPPRERNMV DTAPNTPQSM QRTPKSRPPH RNMSVDNLEF DRLTLERERL EFEKAKIMER 540
  541 ESRLRHEEKQ IEDEKRRMHA EKDLITKETT QPVPPPAAVV THQPITKRYD PPISISPPPQ 600
  601 RNNYSHVKVT VDSDTSPRQQ AFIDDIVAKG GKLAVVTYDR GGQNTKELTV HKGEYLEVIF 660
  661 DERNWWECKN MHQRVGYVPH TILSMVPFEQ QQYASPNHHN NSSSTGGYNN GHHQGPGMLP 720
  721 EDAPSYVKER QGKRGEFRYF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..79] deduced N/A No confident structure predictions are available.
    2 View Details [80..252] PSI-BLAST 55.0 Crystal structure of phosphotyrosine binding (PTB) domain of epidermal growth factor receptor pathway substrate-8 (EPS8) related protein 1 from Mus musculus (form-1 crystal)
    3 View Details [253..559] FFAS03 1.02 No description for 2eyzA was found.
    4 View Details [560..740] PSI-BLAST 28.221849 No description for 2h8hA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  0.597587183571285 bayes_pls_golite062009
  • protein binding
    		•  0.29116370406325 bayes_pls_golite062009
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  0.375837873453985 bayes_pls_golite062009
  • protein binding
    		•  0.25580402341401 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle