Protein Overview: CG4174-PB

General Information:
Name(s) found:	CG4174-PB / FBpp0100021 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|85725184\|ref\|NP_001034032.1\| CG4174, isoform B [Drosophila melanogaster] [NCBI NR] gi\|84796083\|gb\|ABC66131.1\| CG4174, isoform B [Drosophila melanogaster] [NCBI NR] gi\|17862056\|gb\|AAL39505.1\| LD06403p [Drosophila melanogaster] [NCBI NR] This gene is referred to in FlyBase by the symbol Dmel\CG4174 (CG4174, FBgn0036793). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:18593248..18611031. It has the cytological map location 75D3-75D4. Based on sequence similarity, it is predicted to have molecular function</span>: procollagen-proline 4-dioxygenase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: peptidyl-proline hydroxylation to 4-hydroxy-L-proline. One allele is reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase] LD06403p [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:complement(18593446..18593468,18593529..18593676,18593739..18594301,18594364..18594563,18608841..18608944,18609100..18609135); ID=FBpp0100021; name=CG4174-PB; parent=FBgn0036793,FBtr0100566; dbxref=FlyBase_Annotation_IDs:CG4174-PB,Fly [fly-100309-contam.fasta] CG4174-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:complement(18593446..18593468,18593529..18593676,18593739..18594301,18594364..18594563,18608841..18608944,18609100..18609135); ID=FBpp0100021; name=CG4174-PB; parent=FBgn0036793,FBtr0100566; dbxref=FlyBase_Annotation_IDs:CG4174-PB,FlyBase:FBpp0100021,GB_protein:ABC66131.1,REFSEQ:NP_001034032,GB_protein:ABC66131; MD5=bc525028bda9ad95ec7a63365fe51a03; length=357; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:complement(18593446..18593468,18593529..18593676,18593739..18594301,18594364..18594563,18608841..18608944,18609100..18609135); ID=FBpp0100021; name=CG4174-PB; parent=FBgn0036793,FBtr0100566; dbxref=FlyBase_Annotation_IDs:CG4174-PB,FlyBase:FBpp0100021,GB_protein:ABC66131.1,REFSEQ:NP_001034032,GB_protein:ABC66131; MD5=bc525028bda9ad95ec7a63365fe51a03; length=357; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] CG4174, isoform B OS=Drosophila melanogaster GN=CG4174 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=3L:complement(18593446..18593468,18593529..18593676,18593739..18594301,18594364..18594563,18608841..18608944,18609100..18609135); ID=FBpp0100021; name=CG4174-PB; parent=FBgn0036793,FBtr0100566; dbxref=FlyBase_Annotation_IDs:CG4174-PB,FlyBase:FBpp0100021,GB_protein:ABC66131.1,REFSEQ:NP_001034032,GB_protein:ABC66131,FlyMine:FBpp0100021,modMine:FBpp0100021; MD5=bc525028bda9ad95ec7a63365fe51a03; length=357; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
Organism:	Drosophila melanogaster
Length:	357 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum [IEA] procollagen-proline 4-dioxygenase complex [IC]
Biological Process:	oxidation reduction [IEA] peptidyl-proline hydroxylation to 4-hydroxy-L-proline [ISS]
Molecular Function:	procollagen-proline 4-dioxygenase activity [ISS] L-ascorbic acid binding [IEA] oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [IEA] iron ion binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDMHELTAVS KMKGPYFTSQ YFSSQEFPRT NGVTRLRFSL NMLIHISIRN WSADECLMLG  60
   61 LMYLFLKDYN QSENWLELAL YHYDDNVSPE VLKIKLWNYP NLLESLVEAN KGLGHYFEAK 120
  121 KYANELLSIN PNHTYMLTQL PKLKHLQSNP AKLTKPKKVF QLQKEICSKR YRRKSGVLVC 180
  181 RYVDWTPFLK LAPLKMEELS MKPYISIFYG FLGQKDIEVL KNVSRPKLQR IEHLSGNCSC 240
  241 KIGNLSTSLH DVVRKVNELI LGITGFPLKG NQMLEVINYG IAGNYNPEEP KIHNKANAFI 300
  301 FLSNAGKGGE IVFPSRHLKV RPRKGSMLVW ENLKKSLIYH QCPILKGNMW VANKVLN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.94

Protein Overview: CG4174-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: