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Protein Overview: gi|208813668, gi...

General Information:
Name(s) found: gi|208813668 [NCBI NR]
gi|208734945 [NCBI NR]
Description(s) found:
Found 2 descriptions.
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  • gi|208813668|ref|ZP_03254997.1| phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase [Escherichia coli O157:H7 str. EC4045] [NCBI NR]
  • gi|208734945|gb|EDZ83632.1| phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase [Escherichia coli O157:H7 str. EC4045] [NCBI NR]
    • Organism: Escherichia coli O157:H7 str. EC4045
    Length: 430 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKARQQKYCD KIANFWCHPT GKIIMSLAGK KIVLGVSGGI AAYKTPELVR RLRDRGADVR  60
   61 VAMTEAAKAF ITPLSLQAVS GYPVSDSLLD PAAEAAMGHI ELGKWADLVI LAPATADLIA 120
  121 RVAAGMANDL VSTICLATPA PVAVLPAMNQ QMYRAAATQH NLEVLASRGL LIWGPDSGSQ 180
  181 ACGDIGPGRM LDPLTIVDMA VAHFSPVNDL KHLNIMITAG PTREPLDPVR YISNHSSGKM 240
  241 GFAIAAAAAR RGANVTLVSG PVSLPTPPFV KRVDVMTALE MEAAVNASVQ QQNIFIGCAA 300
  301 VADYRAATVA PEKIKKQATQ GDELTIKMVK NPDIVAGVAA LKDHRPYVVG FAAETNNVEE 360
  361 YARQKRIRKN LDLICANDVS QPTQGFNSDN NALHLFWQDG DKVLPLERKE LLGQLLLDEI 420
  421 VTRYDEKNRR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..210] PSI-BLAST 42.0 crystal structure of human phosphopantothenoylcysteine decarboxylase
    2 View Details [211..430] PSI-BLAST 76.045757 Phosphopantothenoylcysteine synthetase from E. coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphopantothenoylcysteine decarboxylase activity
    		•  4.02491392416271 bayes_pls_golite062009
  • phosphopantothenate--cysteine ligase activity
    		•  2.79577339932291 bayes_pls_golite062009
  • 3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
    		•  2.57411029854435 bayes_pls_golite062009
  • carboxy-lyase activity
    		•  2.27469953971238 bayes_pls_golite062009
  • catalytic activity
    		•  1.88716391063227 bayes_pls_golite062009
  • carbon-carbon lyase activity
    		•  1.67751595868044 bayes_pls_golite062009
  • lyase activity
    		•  0.646446561158526 bayes_pls_golite062009
    2
    Term Confidence Notes
  • phosphopantothenate--cysteine ligase activity
    		•  5.84307240498288 bayes_pls_golite062009
  • phosphopantothenoylcysteine decarboxylase activity
    		•  5.6355037343657 bayes_pls_golite062009
  • carboxy-lyase activity
    		•  1.7720171607835 bayes_pls_golite062009
  • catalytic activity
    		•  1.69414665205993 bayes_pls_golite062009
  • carbon-carbon lyase activity
    		•  1.17700977337688 bayes_pls_golite062009
  • ligase activity
    		•  0.75488703247662 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.507933091040939 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.357333622343651 bayes_pls_golite062009
  • lyase activity
    		•  0.155748822211036 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.87

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle