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Protein Overview: gi|31615957

General Information:
Name(s) found: gi|31615957 [NCBI NR]
Description(s) found:
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  • gi|31615957|pdb|1OZN|A Chain A, 1.5a Crystal Structure Of The Nogo Receptor Ligand Binding Domain Reveals A Convergent Recognition Scaffold Mediating Inhibition Of Myelination [NCBI NR]
  • Chain A, 1.5a Crystal Structure Of The Nogo Receptor Ligand Binding Domain Reveals A Convergent Recognition Scaffold Mediating Inhibition Of Myelination [nrdb_11152004_Chlamydomonas]
    • Organism: Homo sapiens
    Length: 285 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PCPGACVCYN EPKVTTSCPQ QGLQAVPVGI PAASQRIFLH GNRISHVPAA SFRACRNLTI  60
   61 LWLHSNVLAR IDAAAFTGLA LLEQLDLSDN AQLRSVDPAT FHGLGRLHTL HLDRCGLQEL 120
  121 GPGLFRGLAA LQYLYLQDNA LQALPDDTFR DLGNLTHLFL HGNRISSVPE RAFRGLHSLD 180
  181 RLLLHQNRVA HVHPHAFRDL GRLMTLYLFA NNLSALPTEA LAPLRALQYL RLNDNPWVCD 240
  241 CRARPLWAWL QKFRGSSSEV PCSLPQRLAG RDLKRLAAND LQGCA

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Noble WS, et al. (2009) Manuscript in preparation. gi|112491310 gi|31615957

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..285] PSI-BLAST 59.69897 Reticulon 4 receptor (Nogo-66 receptor, Ngr)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • extracellular matrix structural constituent
    		•  2.72113902188155 bayes_pls_golite062009
  • binding
    		•  1.87302803330255 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  1.28988458709664 bayes_pls_golite062009
  • extracellular matrix binding
    		•  0.907118880836251 bayes_pls_golite062009
  • protein binding
    		•  0.646159692466759 bayes_pls_golite062009
  • polysaccharide binding
    		•  0.61188190229906 bayes_pls_golite062009
  • receptor binding
    		•  0.525216740013984 bayes_pls_golite062009
  • pattern binding
    		•  0.389630581129679 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.343717562511172 bayes_pls_golite062009
  • receptor activity
    		•  0.269916678721535 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.246718758617065 bayes_pls_golite062009
  • collagen binding
    		•  0.085405748322021 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle