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Protein Overview: gish-PF

General Information:
Name(s) found: gish-PF / FBpp0099736 [FlyBase]
Description(s) found:
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  • gi|62472622|ref|NP_001014628.1| gilgamesh, isoform F [Drosophila melanogaster] [NCBI NR]
  • gi|61679344|gb|AAX52957.1| gilgamesh, isoform F [Drosophila melanogaster] [NCBI NR]
  • gi|25009828|gb|AAN71085.1| AT18609p [Drosophila melanogaster] [NCBI NR]
  • The gene gilgamesh is referred to in FlyBase by the symbol Dmel\gish (CG6963, FBgn0250823). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:12098176..12128094. It has the cytological map location 89B9-89B12. Based on sequence similarity, it is predicted to have molecular function</span>: protein serine/threonine kinase activity. There is experimental evidence that it is involved in the biological process</span>: glial cell migration; protein amino acid phosphorylation; Wnt receptor signaling pathway; spermatogenesis. 48 alleles are reported. The phenotypes of these alleles are annotated with: spermatogonium; eye; photoreceptor cell; ommatidium. It has 9 annotated transcripts and 9 annotated polypeptides. [FlyBase]
  • AT18609p [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:join(12100866..12100891,12115353..12115561,12118446..12118556,12119709..12119875,12122384..12122498,12122558..12122826,12122897..12123067,12123179..12123187); ID=FBpp0099736; name=gish-PF; parent=FBgn0250823,FBtr0100331; dbxref=FlyBas [fly-100309-contam.fasta]
  • CG6963-PF, isoform F [Drosophila melanogaster] [nr-271106-contam.fasta]
  • gilgamesh CG6963-PF, isoform F [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:join(12100866..12100891,12115353..12115561,12118446..12118556,12119709..12119875,12122384..12122498,12122558..12122826,12122897..12123067,12123179..12123187); ID=FBpp0099736; name=gish-PF; parent=FBgn0250823,FBtr0100331; dbxref=FlyBase_Annotation_IDs:CG6963-PF,FlyBase:FBpp0099736,GB_protein:AAX52957.1,REFSEQ:NP_001014628,GB_protein:AAX52957; MD5=e5a64ebb93cdb4ec7e01c8ff81190e12; length=358; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:join(12100866..12100891,12115353..12115561,12118446..12118556,12119709..12119875,12122384..12122498,12122558..12122826,12122897..12123067,12123179..12123187); ID=FBpp0099736; name=gish-PF; parent=FBgn0250823,FBtr0100331; dbxref=FlyBase_Annotation_IDs:CG6963-PF,FlyBase:FBpp0099736,GB_protein:AAX52957.1,REFSEQ:NP_001014628,GB_protein:AAX52957; MD5=e5a64ebb93cdb4ec7e01c8ff81190e12; length=358; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • AT18609p OS=Drosophila melanogaster GN=gish PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:join(12100866..12100891,12115353..12115561,12118446..12118556,12119709..12119875,12122384..12122498,12122558..12122826,12122897..12123067,12123179..12123187); ID=FBpp0099736; name=gish-PF; parent=FBgn0250823,FBtr0100331; dbxref=FlyBase_Annotation_IDs:CG6963-PF,FlyBase:FBpp0099736,GB_protein:AAX52957.1,REFSEQ:NP_001014628,GB_protein:AAX52957,FlyMine:FBpp0099736,modMine:FBpp0099736; MD5=e5a64ebb93cdb4ec7e01c8ff81190e12; length=358; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:join(16275144..16275169,16289631..16289839,16292724..16292834,16293987..16294153,16296662..16296776,16296836..16297104,16297175..16297345,16297457..16297465); ID=FBpp0099736; name=gish-PF; parent=FBgn0250823,FBtr0100331; dbxref=FlyBase_Annotation_IDs:CG6963-PF,FlyBase:FBpp0099736,GB_protein:AAX52957.1,REFSEQ:NP_001014628,GB_protein:AAX52957,FlyMine:FBpp0099736,modMine:FBpp0099736; MD5=e5a64ebb93cdb4ec7e01c8ff81190e12; length=358; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:join(16275144..16275169,16289631..16289839,16292724..16292834,16293987..16294153,16296662..16296776,16296836..16297104,16297175..16297345,16297457..16297465); ID=FBpp0099736; name=gish-PF; parent=FBgn0250823,FBtr0100331; dbxref=FlyBase_Annotation_IDs:CG6963-PF,FlyBase:FBpp0099736,GB_protein:AAX52957.1,REFSEQ:NP_001014628,GB_protein:AAX52957,FlyMine:FBpp0099736,modMine:FBpp0099736; MD5=e5a64ebb93cdb4ec7e01c8ff81190e12; length=358; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of A0A0B4KHL4, AT18609p OS=Drosophila melanogaster GN=gish PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0099736 type=protein; loc=3R:join(16275144..16275169,16289631..16289839,16292724..16292834,16293987..16294153,16296662..16296776,16296836..16297104,16297175..16297345,16297457..16297465); ID=FBpp0099736; name=gish-PF; parent=FBgn0250823,FBtr0100331; dbxref=FlyBase_Annotation_IDs:CG6963-PF,FlyBase:FBpp0099736,GB_protein:AAX52957.1,REFSEQ:NP_001014628,GB_protein:AAX52957,FlyMine:FBpp0099736,modMine:FBpp0099736; MD5=e5a64ebb93cdb4ec7e01c8ff81190e12; length=358; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:join(16275144..16275169,16289631..16289839,16292724..16292834,16293987..16294153,16296662..16296776,16296836..16297104,16297175..16297345,16297457..16297465); ID=FBpp0099736; name=gish-PF; parent=FBgn0250823,FBtr0100331; dbxref=FlyBase_Annotation_IDs:CG6963-PF,FlyBase:FBpp0099736,GB_protein:AAX52957.1,REFSEQ:NP_001014628,GB_protein:AAX52957,UniProt/TrEMBL:Q8IHB0,FlyMine:FBpp0099736,modMine:FBpp0099736; MD5=e5a64ebb93cdb4ec7e01c8ff81190e12; length=358; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 358 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [IDA]
    Biological Process: spermatogenesis [IMP]
    Wnt receptor signaling pathway [IMP]
    protein amino acid phosphorylation [IDA][NAS]
    glial cell migration [IMP]
    Molecular Function: ATP binding [IEA]
    protein serine/threonine kinase activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQRRERQASG GGPQTTTAGP SAGNVANATT ALAGGKSSSN NMYSTRQSVS TTTGVLMVGP  60
   61 NFRVGKKIGC GNFGELRLGK NLYNNEHVAI KMEPMKSKAP QLHLEYRFYK LLGSHADNAP 120
  121 DGIPRIYHLG TCGGRYNAMV LELLGLSLED LFNICARKFS LKTVLMIAKQ LLHRIEYVHS 180
  181 RHLIYRDVKP ENFLIGRTST KREKIIHIID FGLAKEYIDL DTNRHIPYRE HKSLTGTARY 240
  241 MSINTHMGRE QSRRDDLEAL GHMFMYFLRG SLPWQGLKAD TLKERYQKIG DTKRATPIEV 300
  301 LCDGHPEEFA TYLRYVRRLD FFETPDYDFL RRLFQDLFDR KGYTDEGEFD WTGKTMET

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..358] PSI-BLAST 58.045757 No description for 2cmwA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle