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Protein Overview: gi|42566965

General Information:
Name(s) found: gi|42566965 [NCBI NR]
Description(s) found:
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  • gi|42566965|ref|NP_193706.2| bifunctional aspartate kinase/homoserine dehydrogenase, putative / AK-HSDH, putative [Arabidopsis thaliana] [NCBI NR]
  • bifunctional aspartate kinase/homoserine dehydrogenase, putative / AK-HSDH, putative [Arabidopsis thaliana] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Bifunctional aspartate kinase/homoserine dehydrogenase [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: AK-HSDH II, AK-HSDH | AK-HSDH/AK-HSDH II; aspartate kinase/ homoserine dehydrogenase | chr4:10725239-10729288 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • amino acid binding / aspartate kinase/ homoserine dehydrogenase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: AK-HSDH II, AK-HSDH | aspartate kinase-homoserine dehydrogenase ii | chr4:10725229-10729278 FORWARD LENGTH=859 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
  • Isoform 2 of Bifunctional aspartokinase/homoserine dehydrogenase 2, chloroplastic OS=Arabidopsis thaliana GN=AKHSDH2 [ARATH-contam.fasta]
  • Isoform of O81852, Isoform 2 of Bifunctional aspartokinase/homoserine dehydrogenase 2, chloroplastic OS=Arabidopsis thaliana GN=AKHSDH2 [ARATH.fasta.20160308]
    • Organism: Arabidopsis thaliana
    Length: 859 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATLKPSFTV SPPNSNPIRF GSFPPQCFLR VPKPRRLILP RFRKTTGGGG GLIRCELPDF  60
   61 HLSATATTVS GVSTVNLVDQ VQIPKGEMWS VHKFGGTCVG NSQRIRNVAE VIINDNSERK 120
  121 LVVVSAMSKV TDMMYDLIRK AQSRDDSYLS ALEAVLEKHR LTARDLLDGD DLASFLSHLH 180
  181 NDISNLKAML RAIYIAGHAS ESFSDFVAGH GELWSAQMLS YVVRKTGLEC KWMDTRDVLI 240
  241 VNPTSSNQVD PDFGESEKRL DKWFSLNPSK IIIATGFIAS TPQNIPTTLK RDGSDFSAAI 300
  301 MGALLRARQV TIWTDVDGVY SADPRKVNEA VILQTLSYQE AWEMSYFGAN VLHPRTIIPV 360
  361 MRYNIPIVIR NIFNLSAPGT IICQPPEDDY DLKLTTPVKG FATIDNLALI NVEGTGMAGV 420
  421 PGTASDIFGC VKDVGANVIM ISQASSEHSV CFAVPEKEVN AVSEALRSRF SEALQAGRLS 480
  481 QIEVIPNCSI LAAVGQKMAS TPGVSCTLFS ALAKANINVR AISQGCSEYN VTVVIKREDS 540
  541 VKALRAVHSR FFLSRTTLAM GIVGPGLIGA TLLDQLRDQA AVLKQEFNID LRVLGITGSK 600
  601 KMLLSDIGID LSRWRELLNE KGTEADLDKF TQQVHGNHFI PNSVVVDCTA DSAIASRYYD 660
  661 WLRKGIHVIT PNKKANSGPL DQYLKLRDLQ RKSYTHYFYE ATVGAGLPII STLRGLLETG 720
  721 DKILRIEGIC SGTLSYLFNN FVGDRSFSEV VTEAKNAGFT EPDPRDDLSG TDVARKVIIL 780
  781 ARESGLKLDL ADLPIRSLVP EPLKGCTSVE EFMEKLPQYD GDLAKERLDA ENSGEVRLFT 840
  841 TNVFPFDQCD HILTIYICM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..86] deduced N/A No confident structure predictions are available.
    2 View Details [87..554] PSI-BLAST 97.522879 No description for 2hmfA was found.
    3 View Details [555..859] PSI-BLAST 66.221849 Homoserine Dehydrogenase in complex with suicide inhibitor complex NAD-5-hydroxy-4-Oxonorvaline

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • acetolactate synthase activity
    		•  3.48670706716817 bayes_pls_golite062009
  • aspartate kinase activity
    		•  3.23731032633773 bayes_pls_golite062009
  • kinase activity
    		•  2.6815187488202 bayes_pls_golite062009
  • phosphotransferase activity, carboxyl group as acceptor
    		•  2.65970393362911 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.63366715780289 bayes_pls_golite062009
  • amino acid kinase activity
    		•  2.38310367076654 bayes_pls_golite062009
  • transferase activity, transferring aldehyde or ketonic groups
    		•  2.27460110663386 bayes_pls_golite062009
  • acetylglutamate kinase activity
    		•  1.28891782911186 bayes_pls_golite062009
  • catalytic activity
    		•  0.645256181736122 bayes_pls_golite062009
  • transferase activity
    		•  0.576589833246962 bayes_pls_golite062009
  • binding
    		•  0.532494654284107 bayes_pls_golite062009
  • glutamate 5-kinase activity
    		•  0.416864856459166 bayes_pls_golite062009
  • protein binding
    		•  0.066675161728882 bayes_pls_golite062009
    3
    Term Confidence Notes
  • oxidoreductase activity
    		•  2.60548927745815 bayes_pls_golite062009
  • catalytic activity
    		•  2.54843319568228 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  1.54909195188343 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
    		•  0.841370849960815 bayes_pls_golite062009
  • phosphoglycerate dehydrogenase activity
    		•  0.639509916626856 bayes_pls_golite062009
  • saccharopine dehydrogenase activity
    		•  0.495113665163626 bayes_pls_golite062009
  • N-acetyl-gamma-glutamyl-phosphate reductase activity
    		•  0.0651785123513661 bayes_pls_golite062009
  • binding
    		•  0.0273599514394109 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.77

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle