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Protein Overview: gi|18655822

General Information:
Name(s) found: gi|18655822 [NCBI NR]
Description(s) found:
Found 3 descriptions.
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  • gi|18655822|pdb|1H4R|A Chain A, Crystal Structure Of The Ferm Domain Of Merlin, The Neurofibromatosis 2 Tumor Suppressor Protein [NCBI NR]
    • Organism: Homo sapiens
    Length: 314 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GMAGAIASRM SFSSLKRKQP KTFTVRIVTM DAEMEFNCEM KWKGKDLFDL VCRTLGLRET  60
   61 WFFGLQYTIK DTVAWLKMDK KVLDHDVSKE EPVTFHFLAK FYPENAEEEL VQEITQHLFF 120
  121 LQVKKQILDE KIYCPPEASV LLASYAVQAK YGDYDPSVHK RGFLAQEELL PKRVINLYQM 180
  181 TPEMWEERIT AWYAEHRGRA RDEAEMEYLK IAQDLEMYGV NYFAIRNKKG TELLLGVDAL 240
  241 GLHIYDPENR LTPKISFPWN EIRNISYSDK EFTIKPLDKK IDVFKFNSSK LRVNKLILQL 300
  301 CIGNHDLFMR RRKA

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Noble WS, et al. (2009) Manuscript in preparation. gi|112491310 gi|18655822 gi|219109210, gi...

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..314] PSI-BLAST 85.221849 Merlin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.978820612553832 bayes_pls_golite062009
  • protein binding
    		•  0.660521949092081 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle