YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|18655822
Organism:	Homo sapiens
Length:	314 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|18655822.

Description	E-value	Query Range	Subject Range
gi\|114640250 - gi\|114640250\|ref\|XP_522176.2\| PREDICTED: radixin [Pan troglodytes]	315.0	[0..22]	[313..186]
gi\|73994965 - gi\|73994965\|ref\|XP_865563.1\| PREDICTED: similar to neurofibromin 2 isoform 2 isoform 12 [Canis famil...	314.0	[0..2]	[314..1]
gi\|109093780 - gi\|109093780\|ref\|XP_001106361.1\| PREDICTED: similar to neurofibromin 2 isoform 2 isoform 1 [Macaca m... gi\|32451486, gi\|... - gi\|32967266\|ref\|NP_861970.1\| neurofibromin 2 isoform 2 [Homo sapiens], gi\|32967254\|ref\|NP_861546.1\| ...	312.0	[0..2]	[314..1]
MERL_PAPAN - Merlin OS=Papio anubis GN=NF2 PE=3 SV=1 gi\|27819130 - gi\|27819130\|gb\|AAO23133.1\| merlin [Papio anubis anubis]	311.0	[0..2]	[314..1]
gi\|109093778 - gi\|109093778\|ref\|XP_001106489.1\| PREDICTED: similar to neurofibromin 2 isoform 1 isoform 2 [Macaca m...	311.0	[0..2]	[314..1]

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Predicted Domain #1

Region A:
Residues: [1-314]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GMAGAIASRM SFSSLKRKQP KTFTVRIVTM DAEMEFNCEM KWKGKDLFDL VCRTLGLRET  60
   61 WFFGLQYTIK DTVAWLKMDK KVLDHDVSKE EPVTFHFLAK FYPENAEEEL VQEITQHLFF 120
  121 LQVKKQILDE KIYCPPEASV LLASYAVQAK YGDYDPSVHK RGFLAQEELL PKRVINLYQM 180
  181 TPEMWEERIT AWYAEHRGRA RDEAEMEYLK IAQDLEMYGV NYFAIRNKKG TELLLGVDAL 240
  241 GLHIYDPENR LTPKISFPWN EIRNISYSDK EFTIKPLDKK IDVFKFNSSK LRVNKLILQL 300
  301 CIGNHDLFMR RRKA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	85.221849
Match:	1h4rA
Description:	Merlin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.978820612553832	bayes_pls_golite062009
protein binding	0.660521949092081	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: