YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|12851426, gi\|...
Organism:	Mus musculus
Length:	287 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|12851426, gi|....

Description	E-value	Query Range	Subject Range
gi\|53733980 - gb\|AAH83978.1\| Unknown (protein for MGC:98051) [Xenopus laevis] SNRPA_MOUSE - U1 small nuclear ribonucleoprotein A OS=Mus musculus GN=Snrpa PE=1 SV=3	170.0	[0..1]	[287..1]
gi\|34855379, gi\|... - gi\|56605690\|ref\|NP_001008304.1\| small nuclear ribonucleoprotein polypeptide A [Rattus norvegicus], g...	165.0	[0..7]	[287..1]
gi\|208967436 - gi\|208967436\|dbj\|BAG73732.1\| small nuclear ribonucleoprotein polypeptide A [synthetic construct] SNRPA - small nuclear ribonucleoprotein polypeptide A	162.0	[0..7]	[287..1]
gi\|109124828 - gi\|109124828\|ref\|XP_001098504.1\| PREDICTED: small nuclear ribonucleoprotein polypeptide A isoform 7 ... gi\|114677331 - gi\|114677331\|ref\|XP_512674.2\| PREDICTED: hypothetical protein [Pan troglodytes]	162.0	[0..7]	[287..1]
gi\|187607541, gi... - gi\|187607541\|ref\|NP_001119825.1\| small nuclear ribonucleoprotein polypeptide A [Ovis aries], gi\|1841... SNRPA_BOVIN - U1 small nuclear ribonucleoprotein A OS=Bos taurus GN=SNRPA PE=2 SV=1	162.0	[0..7]	[287..1]
SNRPA_PIG - U1 small nuclear ribonucleoprotein A OS=Sus scrofa GN=SNRPA PE=1 SV=1	162.0	[0..7]	[287..1]
gi\|149722301 - gi\|149722301\|ref\|XP_001499386.1\| PREDICTED: similar to U1 small nuclear ribonucleoprotein A (U1 snRN... gi\|73948310 - gi\|73948310\|ref\|XP_533663.2\| PREDICTED: similar to U1 small nuclear ribonucleoprotein A (U1 snRNP pr...	161.0	[0..7]	[287..1]
gi\|38641409, gi\|... - gi\|38641409\|gb\|AAR26269.1\| nuclear ribonucleoprotein A [Oryctolagus cuniculus], gi\|126723082\|ref\|NP_...	160.0	[0..7]	[287..1]
gi\|62857647, gi\|... - gi\|89273875\|emb\|CAJ82017.1\| small nuclear ribonucleoprotein polypeptide A [Xenopus tropicalis], gi\|6...	156.0	[0..7]	[287..1]

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Predicted Domain #1

Region A:
Residues: [1-111]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATIATMPVP ETRANHTIYI NNLNEKIKKD ELKKSLYAIF SQFGQILDIL VSRIMKMRGQ  60
   61 AFVIFKEVTS ATNALRSMQG FPFYDKPMRI QYAKTDSDII AKMKGTYVER D

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	20.522879
Match:	1fhtA
Description:	RNA-BINDING DOMAIN OF THE U1A SPLICEOSOMAL PROTEIN U1A117, NMR, 43 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [112-210]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RKREKRKPKS QETPAAKKAV QVGQLRPWWG LSQPVPGMPP MPQAPRIMHH MPGQPPYMPP  60
   61 PGMIPPPGLA PGQIPPGAMP PQQLMPGQMP PAQPLSENP

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.38
Match:	1pk8A
Description:	Crystal Structure of Rat Synapsin I C Domain Complexed to Ca.ATP
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [211-287]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNHILFLTNL PEETNELMLS MLFNQFPGFK EVRLVPGRHD IAFVEFDNEV QAGAARDALQ  60
   61 GFKITQNNAM KISFAKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	12.30103
Match:	2u1aA
Description:	RNA BINDING DOMAIN 2 OF HUMAN U1A PROTEIN, NMR, 20 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nucleic acid binding	4.50398990564944	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: