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View Structure Prediction Details

Protein: fdl-PB
Organism: Drosophila melanogaster
Length: 673 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for fdl-PB.

Description E-value Query
Range
Subject
Range
FBpp0308698, fdl-PC - The gene fused lobes is referred to in FlyBase by the symbol Dmel\fdl (CG8824, FBgn0045063). It is a...
721.0 [0..14] [673..1]

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Predicted Domain #1
Region A:
Residues: [1-94]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRYVYESLRY LYKMSLAVSL RRALLVLLTG AIFILTVLYW NQGVTKAQAY NEALERPHSH  60
   61 HDASGFPIPV EKSWTYKCEN DRCMRVGHHG KSAK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [95-673]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RVSFISCSMT CGDVNIWPHP TQKFLLSSQT HSFSVEDVQL HVDTAHREVR KQLQLAFDWF  60
   61 LKDLRLIQRL DYVGSSSEPT VSESSSKSRH HADLEPAATL FGATFGVKKA GDLTSVQVKI 120
  121 SVLKSGDLNF SLDNDETYQL STQTEGHRLQ VEIIANSYFG ARHGLSTLQQ LIWFDDEDHL 180
  181 LHTYANSKVK DAPKFRYRGL MLDTSRHFFS VESIKRTIVG MGLAKMNRFH WHLTDAQSFP 240
  241 YISRYYPELA VHGAYSESET YSEQDVREVA EFAKIYGVQV IPEIDAPAHA GNGWDWGPKR 300
  301 GMGELAMCIN QQPWSFYCGE PPCGQLNPKN NYTYLILQRI YEELLQHTGP TDFFHLGGDE 360
  361 VNLDCWAQYF NDTDLRGLWC DFMLQAMARL KLANNGVAPK HVAVWSSALT NTKCLPNSQF 420
  421 TVQVWGGSTW QENYDLLDNG YNVIFSHVDA WYLDCGFGSW RATGDAACAP YRTWQNVYKH 480
  481 RPWERMRLDK KRKKQVLGGE VCMWTEQVDE NQLDNRLWPR TAALAERLWT DPSDDHDMDI 540
  541 VPPDVFRRIS LFRNRLVELG IRAEALFPKY CAQNPGECI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 127.0
Match: 1o7aA
Description: Human beta-Hexosaminidase B
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity, hydrolyzing O-glycosyl compounds 6.26329339735894 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 5.92180849080637 bayes_pls_golite062009
chitinase activity 5.52705867024 bayes_pls_golite062009
galactosidase activity 5.29959220339307 bayes_pls_golite062009
hyalurononglucosaminidase activity 5.08011231554191 bayes_pls_golite062009
alpha-galactosidase activity 4.85819791163713 bayes_pls_golite062009
hexosaminidase activity 4.40461026870613 bayes_pls_golite062009
hydrolase activity 3.5336140444552 bayes_pls_golite062009
mannosidase activity 2.76650385192253 bayes_pls_golite062009
beta-N-acetylhexosaminidase activity 2.69072465526737 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 2.06059323252952 bayes_pls_golite062009
glucosidase activity 1.92306554001182 bayes_pls_golite062009
catalytic activity 1.85569074294201 bayes_pls_golite062009
alpha-amylase activity 1.42264105957213 bayes_pls_golite062009
amylase activity 1.37652764526134 bayes_pls_golite062009
chitin binding 1.29046765706168 bayes_pls_golite062009
signal transducer activity 0.934517587656668 bayes_pls_golite062009
molecular transducer activity 0.934517587656668 bayes_pls_golite062009
mannose binding 0.927066555435524 bayes_pls_golite062009
transporter activity 0.882190348056302 bayes_pls_golite062009
beta-mannosidase activity 0.858618539860091 bayes_pls_golite062009
binding 0.800444849784015 bayes_pls_golite062009
transmembrane transporter activity 0.696239852087965 bayes_pls_golite062009
beta-glucuronidase activity 0.55376725638834 bayes_pls_golite062009
sugar binding 0.52048704356718 bayes_pls_golite062009
alpha-glucosidase activity 0.502835520523619 bayes_pls_golite062009
receptor binding 0.497417763506343 bayes_pls_golite062009
beta-N-acetylglucosaminidase activity 0.489832278458081 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 0.23234868908353 bayes_pls_golite062009
substrate-specific transporter activity 0.223550370855368 bayes_pls_golite062009
carbohydrate binding 0.102788238231918 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 7.36798954279472E-5 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle