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View Structure Prediction Details

Protein: gi|45551023, gi|...
Organism: Drosophila melanogaster
Length: 246 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|45551023, gi|....

Description E-value Query
Range
Subject
Range
gi|32033694 - gi|32033694|ref|ZP_00133989.1| COG0130: Pseudouridine synthase [Actinobacillus pleuropneumoniae sero...
TRUB_ACTP2 - tRNA pseudouridine synthase B OS=Actinobacillus pleuropneumoniae serotype 5b (strain L20) GN=truB PE...
265.0 [0..1] [244..1]

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Predicted Domain #1
Region A:
Residues: [1-246]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALTKVYDAA TVFKHMNGIL NVYKPSGMKV KHVRNAILSN ICKVFGINRG AGQSSSIRKN  60
   61 RPVRVYHLIG HLGIATENNL PDSRVIMRSN HRHVSADRIS SLAASMQASH QRKMFELCGV 120
  121 DLQTQEAYEL ACRGLLRPAD DSQPVVYGIK LIHFDRPHFT LELHAINETQ EYLATLVHDM 180
  181 ALDLRTVAHC SQLRCVRHAH FDVTDSLLRH AWHLPGIIKN LRQQRDILRA HPQLLRQQRV 240
  241 ELRATD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 68.69897
Match: 1r3fA
Description: Crystal Structure of tRNA Pseudouridine Synthase TruB and Its RNA Complex: RNA-protein Recognition Through a Combination of Rigid Docking and Induced Fit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.49175104308599 bayes_pls_golite062009
isomerase activity 0.87098451300632 bayes_pls_golite062009
intramolecular transferase activity 0.86450504855635 bayes_pls_golite062009
pseudouridine synthase activity 0.86297783328106 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle