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View Structure Prediction Details

Protein: CG18528-PA
Organism: Drosophila melanogaster
Length: 493 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG18528-PA.

Description E-value Query
Range
Subject
Range
gi|25319364 - gi|25319364|pir||C86055 hypothetical protein thdF [imported] - Escherichia coli (strain O157:H7, su...
gi|12518545, gi|... - gi|15804300|ref|NP_290339.1| tRNA modification GTPase TrmE [Escherichia coli O157:H7 EDL933], gi|125...
390.0 [0..20] [493..2]

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Predicted Domain #1
Region A:
Residues: [1-493]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALLRNASQS FLGSFRRFAS SGCTIYSLSS GHVKCGVSVI RVSGPQTKKA LRAIVANKEY  60
   61 EPKARQAYLK SFYHPASKEM IDRGLLLWFP GPASFTGEDS CEFQVHGSLA VIAAMLDALG 120
  121 KVDGLRPAEP GEFTKRAFFG GKLDLTEVEG LADLIHAETE AQRKQALLQS TGALARLYDN 180
  181 WRRRLIRCAA HLEAYIDFAE EEQIEGGIIL QLGKELKAVK REIREHLSDQ RQGELLRDGV 240
  241 RTVIIGAPNV GKSSLLNLLC QRSVSIVTDQ AGTTRDIIET MHNFGGYPVV FSDTAGLRRY 300
  301 TTDSIEQEGM QRAKNCLVQS DLILLLAEAK NIAQLTHDDA VAPFVDSYLG ELDIPLDMCS 360
  361 GKRLQLVANK TDTLTDEEHQ QLDKLSNVLA ISCHKPDKMP VFLGSLEKQL QELCGEPRAE 420
  421 NPRITNTRYR QQLERCIENI DIFLRDYRPD VYPDMAIAAS KLRNSVRCIE RITGHISCED 480
  481 ILDVVFKDFC IGK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 86.69897
Match: 1xzpA
Description: Structure of the GTP-binding protein TrmE from Thermotoga maritima
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
methyltransferase activity 3.28983380541263 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 3.20782575104451 bayes_pls_golite062009
catalytic activity 1.65079399897053 bayes_pls_golite062009
transferase activity 1.3676947912529 bayes_pls_golite062009
coenzyme binding 1.08379167900905 bayes_pls_golite062009
nucleic acid binding 0.913322399315129 bayes_pls_golite062009
structural constituent of ribosome 0.738234102557832 bayes_pls_golite062009
RNA helicase activity 0.73539642422624 bayes_pls_golite062009
RNA-dependent ATPase activity 0.70759024918936 bayes_pls_golite062009
ATP-dependent RNA helicase activity 0.68122080550778 bayes_pls_golite062009
ATP binding 0.60527666756293 bayes_pls_golite062009
binding 0.604868700215668 bayes_pls_golite062009
aminomethyltransferase activity 0.573831999310668 bayes_pls_golite062009
adenyl ribonucleotide binding 0.573214556107072 bayes_pls_golite062009
ligase activity 0.417681194526243 bayes_pls_golite062009
transcription regulator activity 0.390949264169589 bayes_pls_golite062009
DNA binding 0.376487324624615 bayes_pls_golite062009
translation regulator activity 0.29096092258568 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.274994961137851 bayes_pls_golite062009
structural molecule activity 0.0558641287316701 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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