| Protein: | loco-PA |
| Organism: | Drosophila melanogaster |
| Length: | 1008 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for loco-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
702.0 | [0..1] | [1008..534] |
|
Region A: Residues: [1-225] |
1 11 21 31 41 51
| | | | | |
1 MPDHSALLRS PPASSSLRRP NLLASFNLIQ SPATNLTSTR SCDDVLNLFV DDSPRTLAAV 60
61 ASMDDISLHS AAPSLDEGHT FAHPACVPRK MRRSLALETP TTPHKLSAQV FGQPGSRHSL 120
121 GFEAIDSVQS SVSGACMDQT MDTWASLQNL HKSHKDRTSM SASSSSHCLL EATNSEPDLG 180
181 NRALPANASP FRRAWGQSSF RTPRSDKVAK EQQQLGQSSP VRRTA
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [226-417] |
1 11 21 31 41 51
| | | | | |
1 SMNASDNDMY IKTLMLDSDL KSSRSQHQLS LLQVPKVLTT PAPPSAITAS VAAEGAAQDH 60
61 GCPSSWAGSF ERMLQDAAGM QTFSEFLKKE FSAENIYFWT ACERYRLLES EADRVAQARE 120
121 IFAKHLANNS SDPVNVDSQA RSLTEEKLAD AAPDIFAPAQ KQIFSLMKFD SYQRFIRSDL 180
181 YKSCVEAEQK NQ
|
| Detection Method: | |
| Confidence: | 57.0 |
| Match: | 1agrE |
| Description: | Regulator of G-protein signalling 4, RGS4 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| GTPase regulator activity | 1.92987277493861 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 1.90800479999702 | bayes_pls_golite062009 |
| GTPase activator activity | 1.87534424848905 | bayes_pls_golite062009 |
| binding | 1.71250041369331 | bayes_pls_golite062009 |
| enzyme activator activity | 1.62073651679221 | bayes_pls_golite062009 |
| enzyme regulator activity | 1.49796137854909 | bayes_pls_golite062009 |
| protein binding | 1.34804002381061 | bayes_pls_golite062009 |
| signal transducer activity | 1.14361809679544 | bayes_pls_golite062009 |
| molecular transducer activity | 1.14361809679544 | bayes_pls_golite062009 |
| beta-catenin binding | 0.59248827140739 | bayes_pls_golite062009 |
|
Region A: Residues: [418-521] |
1 11 21 31 41 51
| | | | | |
1 PLPYSGLDLD ELLKTNFHLG AFSKLKKSAS NAEDRRRKSL LPWHRKTRSK SRDRTEIMAD 60
61 MQHALMPAPP VPQNAPLTSA SLKLVCGQNS LSDLHSSRSS LSSF
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [522-615] |
1 11 21 31 41 51
| | | | | |
1 DAGTATGGQG ASTESVYSLC RVILTDGATT IVQTRPGETV GELVERLLEK RNLVYPYYDI 60
61 VFQGSTKSID VQQPSQILAG KEVVIERRVA FKLD
|
| Detection Method: | |
| Confidence: | 4.31 |
| Match: | 1rrbA |
| Description: | THE RAS-BINDING DOMAIN OF RAF-1 FROM RAT, NMR, 1 STRUCTURE |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| cytoskeletal protein binding | 3.28306198153429 | bayes_pls_golite062009 |
| binding | 2.0688320293797 | bayes_pls_golite062009 |
| protein binding | 1.72968950672856 | bayes_pls_golite062009 |
| signal transducer activity | 1.07208466109379 | bayes_pls_golite062009 |
| molecular transducer activity | 1.07208466109379 | bayes_pls_golite062009 |
| receptor binding | 0.286966350616338 | bayes_pls_golite062009 |
|
Region A: Residues: [616-700] |
1 11 21 31 41 51
| | | | | |
1 LPDPKVISVK SKPKKQLHEV IRPILSKYNY KMEQVQVIMR DTQVPIDLNQ PVTMADGQRL 60
61 RIVMVNSDFQ VGGGSSMPPK QSKPM
|
| Detection Method: | |
| Confidence: | 11.0 |
| Match: | 1wfyA |
| Description: | Solution structure of the Ras-binding domain of mouse RGS14 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| cytoskeletal protein binding | 3.3713276381973 | bayes_pls_golite062009 |
| binding | 2.14676646738549 | bayes_pls_golite062009 |
| protein binding | 1.86841453215444 | bayes_pls_golite062009 |
| signal transducer activity | 1.05682194741929 | bayes_pls_golite062009 |
| molecular transducer activity | 1.05682194741929 | bayes_pls_golite062009 |
| receptor binding | 0.298046142314417 | bayes_pls_golite062009 |
|
Region A: Residues: [701-797] |
1 11 21 31 41 51
| | | | | |
1 KPLPQGHLDE LTNKVFNELL ASKADAAASE KSRPVDLCSM KSNEAPSETS SLFERMRRQQ 60
61 RDGGNIPASK LPKLKKKSTS SSQQSEEAAT TQAVADP
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [798-1008] |
1 11 21 31 41 51
| | | | | |
1 KKPIIAKLKA GVKLQVTERV AEHQDELLEG LKRAQLARLE DQRGTEINFD LPDFLKNKEN 60
61 LSAAVSKLRK VRASLSPVSK VPATPTEIPQ PAPRLSITRS QQPVSPMKVD QEPETDLPAA 120
121 TQDQTEFAKA PPPLPPKPKV LPIKPSNWGV AQPTGNYCNK YSPSKQVPTS PKEASKPGTF 180
181 ASKIPLDLGR KSLEEAGSRC AYLDEPSSSF V
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
