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View Structure Prediction Details

Protein: srp-PA
Organism: Drosophila melanogaster
Length: 1264 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for srp-PA.

Description E-value Query
Range
Subject
Range
gi|39592304, gi|... - gi|39592304|emb|CAE75525.1| Hypothetical protein CBG23547 [Caenorhabditis briggsae], gi|187020927|em...
gi|157762282 - gi|157762282|ref|XP_001673483.1| Hypothetical protein CBG23547 [Caenorhabditis briggsae AF16]
434.0 [0..2] [1246..284]

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Predicted Domain #1
Region A:
Residues: [1-184]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKTTKPKEK AAAGGAVIGS GSGLGSVTKA GGGSLLSNAA DSKIRTAKSN NNKRQAGRAA  60
   61 TALAATTTAS ALAATTTAGA TGSNAAANET EIAIETENGE AATPTAAATA AAANLSSLES 120
  121 ARSQALTSVV SETARQAVTT ANASATSTST VTAATEIATA TASDTAATSE AAIDDDPSAI 180
  181 NTNN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [185-358]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNNNSKAQND ASESVKTKVI SYHQSEDQQQ QQQQQAQIYE QQQQFLSQQL ISHHQQEQHQ  60
   61 QAQQQQHQQV VQEQHQASWL AYDLTSGSAA AAAAAAAAAS HPHLFGQFSY PPSHHTPTQL 120
  121 YEHYPSTDPI MRNNFAFYSV YTGGGGGVGV GMTSHEHLAA AAAAAAAVAQ GTTP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [359-477]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NIDEVIQDTL KDECFEDGHS TDYHVLTSVS DMHTLKDSSP YALTHEQLHQ QQHHHQQQLH  60
   61 HHQQQQQQLY HQQQQQQQQQ QHHHHHNNST SSAGGDSPSS SHALSTLQSF TQLTSATQR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [478-592]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSLSPENDAY FAAAQLGSSL QNSSVYAGSL LTQTANGIQY GMQSPNQTQA HLQQQHHQQQ  60
   61 QQQHQQHQQQ QLQQQQQQHH HNQHQHHNSS SSSPGPAGLH HSSSSAATAA AVAAA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [593-770]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TAAVNGHNSS LEDGYGSPRS SHSGGGGGGT LPAFQRIAYP NSGSVERYAP ITNYRGQNDT  60
   61 WFDPLSYATS SSGQAQLGVG VGAGVVSNVI RNGRAISAAN AAAAAAADGT TGRVDPGTFL 120
  121 SASASLSAMA AESGGDFYKP NSFNVGGGGR SKANTSGAAS SYSCPGSNAT SAATSAVA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [771-880]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGTAATAATT LDEHVSRANS RRLSASKRAG LSCSNCHTTH TSLWRRNPAG EPVCNACGLY  60
   61 YKLHSVPRPL TMKKDTIQKR KRKPKGTKSE KSKSKSKNAL NAIMESGSLV 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.69897
Match: 4gatA
Description: Erythroid transcription factor GATA-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.270879137859077 bayes_pls_golite062009

Predicted Domain #7
Region A:
Residues: [881-957]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TNCHNVGVVL DSSQMDVNDD MKPQLDLKPY NSYSSQPQQQ LPQYQQQQQL LMADQHSSAA  60
   61 SSPHSMGSTS LSPSAMS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [958-1126]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HQHQTHPHQQ QQQQLCSGLD MSPNSNYQMS PLNMQQHQQQ QSCSMQHSPS TPTSIFNTPS  60
   61 PTHQLHNNNN NNNNSSIFNN NNNNNSSSNE NNNKLIQKYL QAQQLSSSSN SGSTSDHQLL 120
  121 AQLLPNSITA AAAAAAAAAA AAIKTEALSL TSQANCSTAS AGLMVTSTP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [1127-1264]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTASSTLSSL SHSNIISLQN PYHQAGMTLC KPTRPSPPYY LTPEEDEQPA LIKMEEMDQS  60
   61 QQQQQQQQHQ QQQHGEIMLS RSASLDEHYE LAAFQRHQQQ QQQLQQQTAA LLGQHEQHVT 120
  121 NYAMHKFGVD RETVVKME

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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