YRC Public Data Repository - Protein Structure Prediction

Protein:	Dat-PB
Organism:	Drosophila melanogaster
Length:	275 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Dat-PB.

Description	E-value	Query Range	Subject Range
gi\|194113598, gi... - gi\|195153781\|ref\|XP_002017802.1\| GL17369 [Drosophila persimilis], gi\|194113598\|gb\|EDW35641.1\| GL1736... gi\|54636079\|gb\|E... - GA17346-PA [Drosophila pseudoobscura], GA17346 [Drosophila pseudoobscura pseudoobscura] gi\|125808884, gi... - gi\|54636079\|gb\|EAL25482.1\| GA17346 [Drosophila pseudoobscura pseudoobscura], gi\|125808884\|ref\|XP_001...	194.0	[0..1]	[275..1]
Dat-PA - The gene Dopamine N acetyltransferase is referred to in FlyBase by the symbol Dmel\Dat (CG3318, FBgn... gi\|220944124, gi... - gi\|220953922\|gb\|ACL89504.1\| Dat-PA [synthetic construct], gi\|220944124\|gb\|ACL84605.1\| Dat-PA [synthe...	177.0	[0..36]	[275..1]
gi\|116118448, gi... - gi\|119114505\|ref\|XP_319299.3\| ENSANGP00000022841 [Anopheles gambiae str. PEST], gi\|116118448\|gb\|EAA1...	143.0	[0..48]	[266..18]
gi\|157128321, gi... - gi\|157128321\|ref\|XP_001661400.1\| hypothetical protein AaeL_AAEL011088 [Aedes aegypti], gi\|108872645\|...	132.0	[0..16]	[266..25]
gi\|34915939 - gi\|34915939\|dbj\|BAC87874.1\| arylalkylamine N-acetyltransferase [Periplaneta americana]	130.0	[0..39]	[265..20]
gi\|39582686, gi\|... - gi\|39582686\|emb\|CAE65892.1\| Hypothetical protein CBG11057 [Caenorhabditis briggsae], gi\|187030570\|em...	127.0	[0..53]	[266..1]
CE35793 - status:Confirmed UniProt:O17526 protein_id:AAB63935.2	126.0	[0..53]	[269..8]
gi\|110634458, gi... - gi\|69276818\|ref\|ZP_00612290.1\| GCN5-related N-acetyltransferase:Bacterial regulatory protein, MarR [...	124.0	[0..5]	[244..48]

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Predicted Domain #1

Region A:
Residues: [1-275]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEVQKLPDQS LISSMMLDSR CGLNDLYPIA RLTQKMEDAL TVSGKPAACP VDQDCPYTIE  60
   61 LIQPEDGEAV IAMLKTFFFK DEPLNTFLDL GECKELEKYS LKPLPDNCSY KAVNKKGEII 120
  121 GVFLNGLMRR PSPDDVPEKA ADSCEHPKFK KILSLMDHVE EQFNIFDVYP DEELILDGKI 180
  181 LSVDTNYRGL GIAGRLTERA YEYMRENGIN VYHVLCSSHY SARVMEKLGF HEVFRMQFAD 240
  241 YKPQGEVVFK PAAPHVGIQV MAKEVGPAKA AQTKL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	4.69897
Match:	1s7fA
Description:	RimL- Ribosomal L7/L12 alpha-N-protein acetyltransferase crystal form I (apo)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.34977492703662	bayes_pls_golite062009
transferase activity	1.92514630957121	bayes_pls_golite062009
N-acyltransferase activity	1.84700347747217	bayes_pls_golite062009
transferase activity, transferring acyl groups	1.75772333794819	bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups	1.63399963366073	bayes_pls_golite062009
acyltransferase activity	1.60091210227059	bayes_pls_golite062009
acetyltransferase activity	1.12147423121182	bayes_pls_golite062009
N-acetyltransferase activity	0.796917859235554	bayes_pls_golite062009
arginine N-succinyltransferase activity	0.141144689590571	bayes_pls_golite062009
diamine N-acetyltransferase activity	0.106741334188309	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: