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View Structure Prediction Details

Protein: Tal-PA
Organism: Drosophila melanogaster
Length: 331 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Tal-PA.

Description E-value Query
Range
Subject
Range
gi|157123140, gi... - gi|157123140|ref|XP_001660027.1| transaldolase [Aedes aegypti], gi|108874520|gb|EAT38745.1| transald...
424.0 [0..2] [331..3]

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Predicted Domain #1
Region A:
Residues: [1-331]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSDRTLKKQ KMSVLQELKK ITTIVADTGD FEAINIYKPT DATTNPSLIL SASSMERYQP  60
   61 LVQKAVEYAK GKKGSVSEQV AEAMDYLCVL FGTEILKVVP GRVSTEIDAR LSFDTKKSVE 120
  121 KALKLIALYK SLGVDKERIL IKLASTWEGI KAAEILENEH GVHCNLTLLF SFAQAVACAE 180
  181 AGVTLISPFV GRILDWYVAN TDTKKFEALK DPGVISVTNI YNYYKKFGYK TLVMGASFRN 240
  241 VGEIKALAGC DLLTISPALL KELENETESV VTYLSVSNAK LQDIEKITVD ESRFRWLLNE 300
  301 DAMATDKLSE GIRKFAVDTV KLENLIKTYL K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 118.0
Match: 1f05A
Description: Transaldolase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transferase activity, transferring aldehyde or ketonic groups 3.28746773527289 bayes_pls_golite062009
transaldolase activity 2.77878684721788 bayes_pls_golite062009
catalytic activity 2.67031204377352 bayes_pls_golite062009
fructose-bisphosphate aldolase activity 2.03916133349076 bayes_pls_golite062009
fructose binding 1.42916270771409 bayes_pls_golite062009
porphobilinogen synthase activity 0.658378297259497 bayes_pls_golite062009
binding 0.467753048702448 bayes_pls_golite062009
transferase activity 0.464721888799972 bayes_pls_golite062009
aldehyde-lyase activity 0.351872954170322 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle