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View Structure Prediction Details

Protein: DNAJB12
Organism: Homo sapiens
Length: 375 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DNAJB12.

Description E-value Query
Range
Subject
Range
gi|114631140 - gi|114631140|ref|XP_508164.2| PREDICTED: DnaJ (Hsp40) homolog, subfamily B, member 12 isoform 2 [Pan...
0.0 [1..375] [1..375]
gi|7019854 - gi|7019854|dbj|BAA90896.1| unnamed protein product [Homo sapiens]
0.0 [1..375] [1..375]
gi|73952872 - gi|73952872|ref|XP_861882.1| PREDICTED: similar to DnaJ (Hsp40) homolog, subfamily B, member 12 isof...
0.0 [1..375] [1..373]
gi|83638757 - gi|83638757|gb|AAI09580.1| DNAJB12 protein [Bos taurus]
0.0 [1..373] [1..373]
DJB12_MOUSE - DnaJ homolog subfamily B member 12 OS=Mus musculus GN=Dnajb12 PE=1 SV=2
0.0 [1..375] [1..376]

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Predicted Domain #1
Region A:
Residues: [1-117]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESNKDEAER CISIALKAIQ SNQPDRALRF LEKAQRLYPT PRVRALIESL NQKPQTAGDQ  60
   61 PPPTDTTHAT HRKAGGTDAP SANGEAGGES TKGYTAEQVA AVKRVKQCKD YYEILGV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.30103
Match: 1na0A
Description: Designed protein cTPR3
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [118-208]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRGASDEDLK KAYRRLALKF HPDKNHAPGA TEAFKAIGTA YAVLSNPEKR KQYDQFGDDK  60
   61 SQAARHGHGH GDFHRGFEAD ISPEDLFNMF F

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.522879
Match: 1xblA
Description: NMR STRUCTURE OF THE J-DOMAIN (RESIDUES 2-76) IN THE ESCHERICHIA COLI N-TERMINAL FRAGMENT (RESIDUES 2-108) OF THE MOLECULAR CHAPERONE DNAJ, 20 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 1.53309887293277 bayes_pls_golite062009
binding 1.46542010527547 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [209-375]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGGFPSSNVH VYSNGRMRYT YQQRQDRRDN QGDGGLGVFV QLMPILILIL VSALSQLMVS  60
   61 SPPYSLSPRP SVGHIHRRVT DHLGVVYYVG DTFSEEYTGS SLKTVERNVE DDYIANLRNN 120
  121 CWKEKQQKEG LLYRARYFGD TDMYHRAQKM GTPSCSRLSE VQASLHG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle