YRC Public Data Repository - Protein Structure Prediction

Protein:	WDR41
Organism:	Homo sapiens
Length:	459 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for WDR41.

Description	E-value	Query Range	Subject Range
gi\|186464325, gi... - gi\|23128981\|ref\|ZP_00110817.1\| COG2319: FOG: WD40 repeat [Nostoc punctiforme PCC 73102], gi\|18668187...	0.0	[2..459]	[1168..1640]
gi\|75701503, gi\|... - gi\|75907778\|ref\|YP_322074.1\| ribosome assembly protein 4 (RSA4) [Anabaena variabilis ATCC 29413], gi...	0.0	[2..459]	[1166..1594]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=... gi\|25530855 - pir\|\|AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)	0.0	[3..459]	[903..1374]
gi\|35214926, gi\|... - gi\|37523920\|ref\|NP_927297.1\| WD repeat-containing protein [Gloeobacter violaceus PCC 7421], gi\|35214...	0.0	[3..459]	[604..1033]
gi\|106891559, gi... - gi\|148655047\|ref\|YP_001275252.1\| WD-40 repeat-containing protein [Roseiflexus sp. RS-1], gi\|14856715...	0.0	[2..459]	[196..672]

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Predicted Domain #1

Region A:
Residues: [1-83]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRWLIGGGR EPQGLAEKSP LQTIGEEQTQ NPYTELLVLK AHHDIVRFLV QLDDYRFASA  60
   61 GDDGIVVVWN AQTGEKLLEL NGH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.39794
Match:	2ovpB
Description:	No description for 2ovpB was found.

Predicted Domain #2

Region A:
Residues: [84-459]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TQKITAIITF PSLESCEEKN QLILTASADR TVIVWDGDTT RQVQRISCFQ STVKCLTVLQ  60
   61 RLDVWLSGGN DLCVWNRKLD LLCKTSHLSD TGISALVEIP KNCVVAAVGK ELIIFRLVAP 120
  121 TEGSLEWDIL EVKRLLDHQD NILSLINVND LSFVTGSHVG ELIIWDALDW TMQAYERNFW 180
  181 DPSPQLDTQQ EIKLCQKSND ISIHHFTCDE ENVFAAVGRG LYVYSLQMKR VIACQKTAHD 240
  241 SNVLHVARLP NRQLISCSED GSVRIWELRE KQQLAAEPVP TGFFNMWGFG RVSKQASQPV 300
  301 KKQQENATSC SLELIGDLIG HSSSVEMFLY FEDHGLVTCS ADHLIILWKN GERESGLRSL 360
  361 RLFQKLEENG DLYLAV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	17.39794
Match:	1k8kC
Description:	Arp2/3 complex 41 kDa subunit ARPC1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.145838346152539	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: