| Protein: | TPH1 |
| Organism: | Homo sapiens |
| Length: | 444 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TPH1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..437] | [1..437] |
|
|
0.0 | [1..437] | [1..437] |
|
|
0.0 | [1..437] | [42..478] |
|
|
0.0 | [1..444] | [1..445] |
|
|
0.0 | [1..444] | [1..444] |
|
|
0.0 | [1..444] | [1..444] |
|
|
0.0 | [2..444] | [39..481] |
|
Region A: Residues: [1-95] |
1 11 21 31 41 51
| | | | | |
1 MIEDNKENKD HSLERGRASL IFSLKNEVGG LIKALKIFQE KHVNLLHIES RKSKRRNSEF 60
61 EIFVDCDINR EQLNDIFHLL KSHTNVLSVN LPDNF
|
| Detection Method: |  |
| Confidence: | 23.39794 |
| Match: | 2qmxA |
| Description: | No description for 2qmxA was found. |
|
Region A: Residues: [96-444] |
1 11 21 31 41 51
| | | | | |
1 TLKEDGMETV PWFPKKISDL DHCANRVLMY GSELDADHPG FKDNVYRKRR KYFADLAMNY 60
61 KHGDPIPKVE FTEEEIKTWG TVFQELNKLY PTHACREYLK NLPLLSKYCG YREDNIPQLE 120
121 DVSNFLKERT GFSIRPVAGY LSPRDFLSGL AFRVFHCTQY VRHSSDPFYT PEPDTCHELL 180
181 GHVPLLAEPS FAQFSQEIGL ASLGASEEAV QKLATCYFFT VEFGLCKQDG QLRVFGAGLL 240
241 SSISELKHAL SGHAKVKPFD PKITCKQECL ITTFQDVYFV SESFEDAKEK MREFTKTIKR 300
301 PFGVKYNPYT RSIQILKDTK SITSAMNELQ HDLDVVSDAL AKVSRKPSI
|
| Detection Method: | |
| Confidence: | 153.0 |
| Match: | 1mlwA |
| Description: | Tryptophan hydroxylase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| tyrosine 3-monooxygenase activity | 10.4963678823868 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen | 10.3746889036269 | bayes_pls_golite062009 |
| phenylalanine 4-monooxygenase activity | 5.13697132751033 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | 4.1759203417536 | bayes_pls_golite062009 |
| monooxygenase activity | 3.40046054657404 | bayes_pls_golite062009 |
| tryptophan 5-monooxygenase activity | 3.21197226254744 | bayes_pls_golite062009 |
| oxidoreductase activity | 2.09811280777991 | bayes_pls_golite062009 |
| binding | 1.74682374387162 | bayes_pls_golite062009 |
| amine binding | 1.23106204610034 | bayes_pls_golite062009 |
| catalytic activity | 0.932947046865376 | bayes_pls_golite062009 |
| protein binding | 0.431526081681418 | bayes_pls_golite062009 |
| tetrahydrobiopterin binding | 0.0418066331050291 | bayes_pls_golite062009 |
