YRC Public Data Repository - Protein Structure Prediction

Protein:	SETD3
Organism:	Homo sapiens
Length:	594 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SETD3.

Description	E-value	Query Range	Subject Range
SETD3_MOUSE - Histone-lysine N-methyltransferase setd3 OS=Mus musculus GN=Setd3 PE=1 SV=1	702.0	[0..1]	[594..1]
gi\|149044195, gi... - gi\|149044195\|gb\|EDL97577.1\| rCG27725, isoform CRA_a [Rattus norvegicus], gi\|109479948\|ref\|XP_0010691...	699.0	[0..1]	[594..1]
gi\|114654683 - gi\|114654683\|ref\|XP_522946.2\| PREDICTED: hypothetical protein isoform 2 [Pan troglodytes]	695.0	[0..1]	[594..1]
gi\|109084840 - gi\|109084840\|ref\|XP_001103370.1\| PREDICTED: similar to SET domain containing 3 isoform 3 [Macaca mul...	687.0	[0..1]	[594..1]
gi\|73964462 - gi\|73964462\|ref\|XP_547974.2\| PREDICTED: similar to CG32732-PA [Canis familiaris]	632.0	[0..1]	[594..1]
SETD3_CHICK - Histone-lysine N-methyltransferase setd3 OS=Gallus gallus GN=SETD3 PE=2 SV=1	588.0	[0..1]	[594..1]
gi\|10439587 - gi\|10439587\|dbj\|BAB15525.1\| unnamed protein product [Homo sapiens]	578.0	[0..83]	[594..1]
gi\|89272100, gi\|... - gi\|89272100\|emb\|CAJ81720.1\| novel protein containing a SET domain [Xenopus tropicalis], gi\|62857953\|...	557.0	[0..1]	[584..1]

Back

Predicted Domain #1

Region A:
Residues: [1-500]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKKSRVKTQ KSGTGATATV SPKEILNLTS ELLQKCSSPA PGPGKEWEEY VQIRTLVEKI  60
   61 RKKQKGLSVT FDGKREDYFP DLMKWASENG ASVEGFEMVN FKEEGFGLRA TRDIKAEELF 120
  121 LWVPRKLLMT VESAKNSVLG PLYSQDRILQ AMGNIALAFH LLCERASPNS FWQPYIQTLP 180
  181 SEYDTPLYFE EDEVRYLQST QAIHDVFSQY KNTARQYAYF YKVIQTHPHA NKLPLKDSFT 240
  241 YEDYRWAVSS VMTRQNQIPT EDGSRVTLAL IPLWDMCNHT NGLITTGYNL EDDRCECVAL 300
  301 QDFRAGEQIY IFYGTRSNAE FVIHSGFFFD NNSHDRVKIK LGVSKSDRLY AMKAEVLARA 360
  361 GIPTSSVFAL HFTEPPISAQ LLAFLRVFCM TEEELKEHLL GDSAIDRIFT LGNSEFPVSW 420
  421 DNEVKLWTFL EDRASLLLKT YKTTIEEDKS VLKNHDLSVR AKMAIKLRLG EKEILEKAVK 480
  481 SAAVNREYYR QQMEEKAPLP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	81.0
Match:	1mlvA
Description:	RuBisCo LSMT C-terminal, substrate-binding domain; RuBisCo LSMT catalytic domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [501-594]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KYEESNLGLL ESSVGDSRLP LVLRNLEEEA GVQDALNIRE AISKAKATEN GLVNGENSIP  60
   61 NGTRSENESL NQESKRAVED AKGSSSDSTA GVKE

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits