YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: gi|119628575, gi...
Organism: Homo sapiens
Length: 807 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|119628575, gi....

Description E-value Query
Range
Subject
Range
gi|22759956, gi|... - gi|38201700|ref|NP_937984.1| telomerase reverse transcriptase isoform 4 [Homo sapiens], gi|22759956|...
0.0 [1..807] [1..795]
gi|3023055 - gi|3023055|gb|AAC40212.1| telomerase catalytic subunit [synthetic construct]
0.0 [1..763] [1..763]
gi|114598857 - gi|114598857|ref|XP_001141663.1| PREDICTED: telomerase reverse transcriptase isoform 2 [Pan troglody...
0.0 [1..755] [1..755]
gi|109076635 - gi|109076635|ref|XP_001096904.1| PREDICTED: similar to telomerase reverse transcriptase isoform 1 is...
0.0 [1..763] [1..763]

Back

Predicted Domain #1
Region A:
Residues: [1-214]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPRAPRCRAV RSLLRSHYRE VLPLATFVRR LGPQGWRLVQ RGDPAAFRAL VAQCLVCVPW  60
   61 DARPPPAAPS FRQVSCLKEL VARVLQRLCE RGAKNVLAFG FALLDGARGG PPEAFTTSVR 120
  121 SYLPNTVTDA LRGSGAWGLL LRRVGDDVLV HLLARCALFV LVAPSCAYQV CGPPLYQLGA 180
  181 ATQARPPPHA SGPRRRLGCE RAWNHSVREA GVPL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.02
Match: 2b2aA
Description: Crystal Structure of the TEN domain of the Telomerase Reverse Transcriptase
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [215-455]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLPAPGARRR GGSASRSLPL PKRPRRGAAP EPERTPVGQG SWAHPGRTRG PSDRGFCVVS  60
   61 PARPAEEATS LEGALSGTRH SHPSVGRQHH AGPPSTSRPP RPWDTPCPPV YAETKHFLYS 120
  121 SGDKEQLRPS FLLSSLRPSL TGARRLVETI FLGSRPWMPG TPRRLPRLPQ RYWQMRPLFL 180
  181 ELLGNHAQCP YGVLLKTHCP LRAAVTPAAG VCAREKPQGS VAAPEEEDTD PRRLVQLLRQ 240
  241 H

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [456-567]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSPWQVYGFV RACLRRLVPP GLWGSRHNER RFLRNTKKFI SLGKHAKLSL QELTWKMSVR  60
   61 DCAWLRRSPG VGCVPAAEHR LREEILAKFL HWLMSVYVVE LLRSFFYVTE TT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [568-640]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FQKNRLFFYR KSVWSKLQSI GIRQHLKRVQ LRELSEAEVR QHREARPALL TSRLRFIPKP  60
   61 DGLRPIVNMD YVV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.692 N/A N/A a.46.1 Methionine synthase domain
View Download 0.675 N/A N/A a.7.6 Ribosomal protein S20
View Download 0.656 N/A N/A a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.627 N/A N/A a.46.1 Methionine synthase domain
View Download 0.601 N/A N/A a.46.1 Methionine synthase domain

Predicted Domain #5
Region A:
Residues: [641-702]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GARTFRREKR AERLTSRVKA LFSVLNYERA RRPGLLGASV LGLDDIHRAW RTFVLRVRAQ  60
   61 DP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.814 N/A N/A a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.577 N/A N/A a.5.6 Hypothetical protein MTH1615
View Download 0.549 N/A N/A a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.534 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.510 N/A N/A a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3

Predicted Domain #6
Region A:
Residues: [703-807]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPELYFVKVD VTGAYDTIPQ DRLTEVIASI IKPQNTYCVR RYAVVQKAAH GHVRKAFKSH  60
   61 VLRPVPGDPA GLHPLHAALQ PVLRRHGEQA VCGDSAGRAA PAFGG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.718 N/A N/A c.47.1 Thioredoxin-like
View Download 0.536 N/A N/A a.118.11 Cytochrome c oxidase subunit E
View Download 0.517 N/A N/A d.68.6 DNA-binding protein Sso10b (AlbA)
View Download 0.478 N/A N/A a.118.11 Cytochrome c oxidase subunit E
View Download 0.451 N/A N/A c.95.1 Thiolase-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle