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View Structure Prediction Details

Protein: STOM
Organism: Homo sapiens
Length: 288 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for STOM.

Description E-value Query
Range
Subject
Range
gi|60831910 - gi|60831910|gb|AAX36989.1| stomatin [synthetic construct]
3.0E-74 [1..288] [1..288]
gi|109110361 - gi|109110361|ref|XP_001090776.1| PREDICTED: stomatin isoform 2 [Macaca mulatta]
CCDS6830.1_1 - null
1.0E-73 [1..288] [1..288]
gi|14715077 - gi|14715077|gb|AAH10703.1| Stomatin [Homo sapiens]
2.0E-73 [1..288] [1..288]
gi|50757151 - gi|50757151|ref|XP_415401.1| PREDICTED: similar to Erythrocyte band 7 integral membrane protein (Sto...
1.0E-72 [14..283] [387..656]
gi|975689, gi|21... - gi|975689|emb|CAA62503.1| erthyrocyte band 7 integral membrane protein, protein 7.2B, stomatin [Mus ...
1.0E-69 [1..282] [1..282]
gi|149038926, gi... - gi|58865500|ref|NP_001011965.1| stomatin [Rattus norvegicus], gi|54035354|gb|AAH83895.1| Stomatin [R...
2.0E-69 [1..282] [1..282]
gi|73972043 - gi|73972043|ref|XP_855536.1| PREDICTED: similar to Erythrocyte band 7 integral membrane protein (Sto...
5.0E-69 [22..284] [42..304]

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Predicted Domain #1
Region A:
Residues: [1-78]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEKRHTRDS EAQRLPDSFK DSPSKGLGPC GWILVAFSFL FTVITFPISI WMCIKIIKEY  60
   61 ERAIIFRLGR ILQGGAKG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [79-288]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PGLFFILPCT DSFIKVDMRT ISFDIPPQEI LTKDSVTISV DGVVYYRVQN ATLAVANITN  60
   61 ADSATRLLAQ TTLRNVLGTK NLSQILSDRE EIAHNMQSTL DDATDAWGIK VERVEIKDVK 120
  121 LPVQLQRAMA AEAEASREAR AKVIAAEGEM NASRALKEAS MVITESPAAL QLRYLQTLTT 180
  181 IAAEKNSTIV FPLPIDMLQG IIGAKHSHLG 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.154902
Match: 1winA
Description: Solution Structure of the Band 7 Domain of the mouse Flotillin 2 Protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
structural molecule activity 0.834496144484266 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle