YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|5102630, gi\|2...
Organism:	Homo sapiens
Length:	492 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|5102630, gi|2....

Description	E-value	Query Range	Subject Range
HGNC:5003\|MIM:60... - box domain containing 4 gi\|208967869, gi... - gi\|208967869\|dbj\|BAG72580.1\| high-mobility group protein 2-like 1 [synthetic construct], gi\|10945192... HMGXB4 - HMG box domain containing 4	2.0E-67	[1..492]	[110..601]
gi\|114686112 - gi\|114686112\|ref\|XP_515098.2\| PREDICTED: high-mobility group protein 2-like 1 isoform 4 [Pan troglod...	3.0E-67	[1..492]	[110..601]
gi\|30794254, gi\|... - gi\|30794254\|ref\|NP_821136.1\| HMG box domain containing 4 [Mus musculus], gi\|29436851\|gb\|AAH49800.1\| ...	4.0E-67	[1..492]	[110..594]
gi\|76619085 - gi\|76619085\|ref\|XP_886550.1\| PREDICTED: similar to high-mobility group protein 2-like 1 isoform b is...	3.0E-66	[1..492]	[106..598]
gi\|109508402, gi... - ref\|XP_226315.2\| similar to High mobility group box 2-like 1 [Rattus norvegicus], gi\|109508402\|ref\|X...	3.0E-66	[1..492]	[110..594]
gi\|109093991 - gi\|109093991\|ref\|XP_001113091.1\| PREDICTED: similar to high-mobility group protein 2-like 1 isoform ...	6.0E-66	[1..492]	[110..601]
gi\|73969226 - gi\|73969226\|ref\|XP_850802.1\| PREDICTED: similar to high-mobility group protein 2-like 1 isoform b is...	4.0E-65	[1..492]	[110..600]

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Predicted Domain #1

Region A:
Residues: [1-187]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLLKAITSP LAAGSKPSKK TGEKSSGSSS HSESKKEHHR KKVSGSSGEL PLEDGGSHKS  60
   61 KKMKPLYVNT ETLTLREPDG LKMKLILSPK EKGSSSVDEE SFQYPSQQAT VKKSSKKSAR 120
  121 DEQGALLLGH ELQSFLKTAR KKHKSSSDAH SSPGPEGCGS DASQFAESHS ANLDLSGLEP 180
  181 ILVESDS

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [188-283]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSGGELEAGE LVIDDSYREI KKKKKSKKSK KKKDKEKHKE KRHSKSKRSL GLSAVPVGEV  60
   61 TVTSGPPPSI PYAGAAAPPL PLPGLHTDGH SEKKKK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [284-492]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KEEKDKERER GEKPKKKNMS AYQVFCKEYR VTIVADHPGI DFGELSKKLA EVWKQLPEKD  60
   61 KLIWKQKAQY LQHKQNKAEA TTVKRKASSS EGSMKVKASS VGVLSPQKKS PPTTMLLPAS 120
  121 PAKAPETEPI DVAAHLQLLG ESLSLIGHRL QETEGMVAVS GSLSVLLDSI ICALGPLACL 180
  181 TTQLPELNGC PKQVLSNTLD NIAYIMPGL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	27.69897
Match:	2gzkA
Description:	No description for 2gzkA was found.

Predicted functions:

Term	Confidence	Notes
binding	0.927928103499335	bayes_pls_golite062009
nucleic acid binding	0.38664561645052	bayes_pls_golite062009
DNA binding	0.37554038880732	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: