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View Structure Prediction Details

Protein: gi|22202624, gi|...
Organism: Homo sapiens
Length: 216 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|22202624, gi|....

Description E-value Query
Range
Subject
Range
MAAI_RAT - Maleylacetoacetate isomerase OS=Rattus norvegicus GN=Gstz1 PE=1 SV=2
1.0E-51 [1..215] [1..215]
gi|3510757, gi|3... - gi|3510757|gb|AAC33591.1| glutathione transferase zeta 1 [Homo sapiens], gi|32140477|gb|AAP69526.1| ...
3.0E-51 [1..216] [1..216]
gi|50748528 - gi|50748528|ref|XP_421288.1| PREDICTED: hypothetical protein isoform 3 [Gallus gallus]
3.0E-51 [1..216] [1..215]
gi|109084410 - gi|109084410|ref|XP_001101990.1| PREDICTED: similar to glutathione transferase zeta 1 isoform 1 isof...
4.0E-51 [1..216] [1..216]
MAAI_MOUSE - Maleylacetoacetate isomerase OS=Mus musculus GN=Gstz1 PE=1 SV=1
1.0E-50 [1..215] [1..215]
gi|71834680, gi|... - gi|71834680|ref|NP_001025442.1| glutathione transferase zeta 1 isoform 1 [Danio rerio], gi|66910381|...
5.0E-50 [1..215] [1..215]

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Predicted Domain #1
Region A:
Residues: [1-216]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQAGKPILYS YFRSSCSWRV RIALALKGID YETVPINLIK DGGQQFSKDF QALNPMKQVP  60
   61 TLKIDGITIH QSLAIIEYLE EMRPTPRLLP QDPKKRASVR MISDLIAGGI QPLQNLSVLK 120
  121 QVGEEMQLTW AQNAITCGFN ALEQILQSTA GIYCVGDEVT MADLCLVPQV ANAERFKVDL 180
  181 TPYPTISSIN KRLLVLEAFQ VSHPCRQPDT PTELRA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 52.154902
Match: 1fw1A
Description: Class zeta GST
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
antioxidant activity 3.8464796631544 bayes_pls_golite062009
peroxidase activity 3.43831566988273 bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor 3.43831566988273 bayes_pls_golite062009
glutathione peroxidase activity 2.56524997297011 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 2.23310780102446 bayes_pls_golite062009
peroxiredoxin activity 2.12777217096121 bayes_pls_golite062009
glutathione binding 2.07086805531749 bayes_pls_golite062009
thioredoxin peroxidase activity 1.96134566495756 bayes_pls_golite062009
glutathione transferase activity 1.85683051472829 bayes_pls_golite062009
oxidoreductase activity 1.71351657881838 bayes_pls_golite062009
transcription regulator activity 1.70971346870415 bayes_pls_golite062009
DNA binding 1.33036936239597 bayes_pls_golite062009
disulfide oxidoreductase activity 1.32811008894503 bayes_pls_golite062009
nucleic acid binding 1.17582289196382 bayes_pls_golite062009
binding 0.828696005067827 bayes_pls_golite062009
catalytic activity 0.672192331361968 bayes_pls_golite062009
protein binding 0.134341907247724 bayes_pls_golite062009
protein disulfide oxidoreductase activity 0.0719543694089202 bayes_pls_golite062009

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