YRC Public Data Repository - Protein Structure Prediction

Protein:	YNFM_ECOLI
Organism:	Escherichia coli
Length:	417 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YNFM_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|110827356, gi... - gi\|111615223\|ref\|ZP_01402289.1\| Sugar phosphate permease-like [Verminephrobacter eiseniae EF01-2], g...	191.0	[0..3]	[415..269]
gi\|218202668 - gi\|218202668\|gb\|EEC85095.1\| hypothetical protein OsI_32467 [Oryza sativa Indica Group] PHT44_ORYSJ - Probable anion transporter 4, chloroplastic OS=Oryza sativa subsp. japonica GN=PHT4;4 PE=2 SV=1	188.0	[0..1]	[411..148]
gi\|50260260, gi\|... - gi\|50260260\|gb\|EAL22919.1\| hypothetical protein CNBA6880 [Cryptococcus neoformans var. neoformans B-...	182.0	[0..3]	[413..78]
gi\|68389434 - gi\|68389434\|ref\|XP_691920.1\| PREDICTED: similar to solute carrier family 17 (sodium-dependent inorga...	177.0	[0..32]	[412..141]
gi\|39944294, gi\|... - gi\|39944294\|ref\|XP_361684.1\| hypothetical protein MGG_04158 [Magnaporthe grisea 70-15], gb\|EAA50399....	177.0	[0..20]	[413..121]
gi\|78495751, gi\|... - gi\|78495751\|ref\|ZP_00847969.1\| Major facilitator superfamily MFS_1 [Rhodopseudomonas palustris BisB1...	176.0	[0..15]	[416..430]
ANTR2_ARATH - Ascorbate transporter, chloroplastic OS=Arabidopsis thaliana GN=PHT4;4 PE=1 SV=1	173.0	[0..4]	[412..102]
gi\|49650092 - gi\|49650092\|emb\|CAG79818.1\| YALI0E21241p [Yarrowia lipolytica] gi\|49650092, gi\|... - gi\|50553624\|ref\|XP_504223.1\| YALI0E21241p [Yarrowia lipolytica], gi\|49650092\|emb\|CAG79818.1\| unnamed...	172.0	[0..20]	[415..123]

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Predicted Domain #1

Region A:
Residues: [1-417]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRTTTVDGA PASDTDKQSI SQPNQFIKRG TPQFMRVTLA LFSAGLATFA LLYCVQPILP  60
   61 VLSQEFGLTP ANSSISLSIS TAMLAIGLLF TGPLSDAIGR KPVMVTALLL ASICTLLSTM 120
  121 MTSWHGILIM RALIGLSLSG VAAVGMTYLS EEIHPSFVAF SMGLYISGNS IGGMSGRLIS 180
  181 GVFTDFFNWR IALAAIGCFA LASALMFWKI LPESRHFRPT SLRPKTLFIN FRLHWRDRGL 240
  241 PLLFAEGFLL MGSFVTLFNY IGYRLMLSPW HVSQAVVGLL SLAYLTGTWS SPKAGTMTTR 300
  301 YGRGPVMLFS TGVMLFGLLM TLFSSLWLIF AGMLLFSAGF FAAHSVASSW IGPRAKRAKG 360
  361 QASSLYLFSY YLGSSIAGTL GGVFWHNYGW NGVGAFIALM LVIALLVGTR LHRRLHA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	30.30103
Match:	1pw4A
Description:	Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transporter activity	4.09176719149278	bayes_pls_golite062009
transmembrane transporter activity	3.5865018981083	bayes_pls_golite062009
substrate-specific transporter activity	3.3426261924492	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	3.29689809004391	bayes_pls_golite062009
ion transmembrane transporter activity	1.94035843948137	bayes_pls_golite062009
active transmembrane transporter activity	1.59419818573076	bayes_pls_golite062009
cation transmembrane transporter activity	1.5181741634556	bayes_pls_golite062009
secondary active transmembrane transporter activity	1.22264637452409	bayes_pls_golite062009
polyol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
alcohol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
glycerol transmembrane transporter activity	0.812001619402678	bayes_pls_golite062009
binding	0.805286077372817	bayes_pls_golite062009
symporter activity	0.74591237387473	bayes_pls_golite062009
solute:cation symporter activity	0.74591237387473	bayes_pls_golite062009
sugar:hydrogen symporter activity	0.143419068761182	bayes_pls_golite062009
cation:sugar symporter activity	0.143419068761182	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: