YRC Public Data Repository - Protein Structure Prediction

Protein:	YNBC_ECOLI
Organism:	Escherichia coli
Length:	585 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YNBC_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|192959781, gi... - gi\|75239962\|ref\|ZP_00723923.1\| COG0500: SAM-dependent methyltransferases [Escherichia coli E110019],...	379.0	[0..1]	[585..1]
gi\|157066568, gi... - gi\|75195523\|ref\|ZP_00705593.1\| COG0500: SAM-dependent methyltransferases [Escherichia coli HS], gi\|1...	378.0	[0..1]	[585..1]
gi\|75515003, gi\|... - gi\|75515003\|ref\|ZP_00737207.1\| COG0500: SAM-dependent methyltransferases [Escherichia coli 53638], g... gi\|124499903, gi... - gi\|124529445\|ref\|ZP_01700449.1\| Methyltransferase type 12 [Escherichia coli B], gi\|124499903\|gb\|EAY4... gi\|169755186, gi... - gi\|170020258\|ref\|YP_001725212.1\| hypothetical protein EcolC_2248 [Escherichia coli ATCC 8739], gi\|16...	378.0	[0..1]	[585..1]
gi\|193062575, gi... - gi\|75259531\|ref\|ZP_00730850.1\| COG0500: SAM-dependent methyltransferases [Escherichia coli E22], gi\|...	376.0	[0..1]	[585..1]
gi\|75212818, gi\|... - gi\|75212818\|ref\|ZP_00712816.1\| COG0500: SAM-dependent methyltransferases [Escherichia coli B171], gi...	375.0	[0..1]	[585..1]
gi\|208741161, gi... - gi\|208821038\|ref\|ZP_03261358.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4042... gi\|208731488, gi... - gi\|208814840\|ref\|ZP_03256019.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4045... gi\|208724360, gi... - gi\|208810854\|ref\|ZP_03252687.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4206... gi\|13361478, gi\|... - gi\|15831266\|ref\|NP_310039.1\| hypothetical protein ECs2012 [Escherichia coli O157:H7 str. Sakai], gi\|... gi\|195938027 - gi\|195938027\|ref\|ZP_03083409.1\| hypothetical protein EscherichcoliO157_16607 [Escherichia coli O157:... gi\|217317598, gi... - gi\|217329159\|ref\|ZP_03445239.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. TW1458... gi\|209158436, gi... - gi\|209397036\|ref\|YP_002270419.1\| hypothetical protein ECH74115_2013 [Escherichia coli O157:H7 str. E... gi\|189361542, gi... - gi\|189361542\|gb\|EDU79961.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4486], g... gi\|189366650, gi... - gi\|189366650\|gb\|EDU85066.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501], g... gi\|168756049, gi... - gi\|189356811\|gb\|EDU75230.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4401], g... gi\|168748993, gi... - gi\|188016617\|gb\|EDU54739.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4113], g... gi\|189377941, gi... - gi\|189377941\|gb\|EDU96357.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC508], gi... gi\|189371860, gi... - gi\|189371860\|gb\|EDU90276.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC869], gi... gi\|168782898, gi... - gi\|188999670\|gb\|EDU68656.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4076], g... gi\|187767518, gi... - gi\|187767518\|gb\|EDU31362.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4196], g... gi\|254792954, gi... - gi\|254792954\|ref\|YP_003077791.1\| predicted hydrolase [Escherichia coli O157:H7 str. TW14359], gi\|254... gi\|25390613, gi\|... - pir\|\|E85738 hypothetical protein Z2317 [imported] - Escherichia coli (strain O157:H7, substrain EDL... gi\|15801737, gi\|... - gi\|15801737\|ref\|NP_287755.1\| hypothetical protein Z2317 [Escherichia coli O157:H7 EDL933], gi\|125153... gi\|13361478, gi\|... - gi\|15831266\|ref\|NP_310039.1\| hypothetical protein ECs2012 [Escherichia coli O157:H7], gi\|13361478\|db...	374.0	[0..1]	[585..1]
gi\|24113158, gi\|... - gi\|24113158\|ref\|NP_707668.1\| hypothetical protein SF1808 [Shigella flexneri 2a str. 301], gi\|2405214... gi\|30062881, gi\|... - gi\|30062881\|ref\|NP_837052.1\| hypothetical protein S1466 [Shigella flexneri 2a str. 2457T], gi\|300411... gi\|110615294, gi... - gi\|110805746\|ref\|YP_689266.1\| hypothetical protein SFV_1799 [Shigella flexneri 5 str. 8401], gi\|1106...	373.0	[0..1]	[585..1]
gi\|157154972, gi... - gi\|75190462\|ref\|ZP_00703729.1\| COG0500: SAM-dependent methyltransferases [Escherichia coli E24377A],...	373.0	[0..1]	[585..1]
gi\|81241184, gi\|... - gi\|82777036\|ref\|YP_403385.1\| hypothetical protein SDY_1779 [Shigella dysenteriae Sd197], gi\|81241184...	370.0	[0..1]	[585..1]
gi\|73855718, gi\|... - gi\|74312241\|ref\|YP_310660.1\| hypothetical protein SSON_1736 [Shigella sonnei Ss046], gi\|73855718\|gb\|...	369.0	[0..1]	[585..1]

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Predicted Domain #1

Region A:
Residues: [1-286]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENSRIPGEH FFTTSDNTAL FYRHWPALQP GAKKVIVLFH RGHEHSGRLQ HLVDELAMPD  60
   61 TAFYAWDARG HGKSSGPRGY SPSLARSVRD VDEFVRFAAS DSQVGLEEVV VIAQSVGAVL 120
  121 VATWIHDYAP AIRGLVLASP AFKVKLYVPL ARPALALWHR LRGLFFINSY VKGRYLTHDR 180
  181 QRGASFNNDP LITRAIAVNI LLDLYKTSER IIRDAAAITL PTQLLISGDD YVVHRQPQID 240
  241 FYQRLRSPLK ELHLLPGFYH DTLGEENRAL AFEKMQSFIS RLYANK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	38.522879
Match:	1a8sA
Description:	CHLOROPEROXIDASE F/PROPIONATE COMPLEX
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.39629727416851	bayes_pls_golite062009
hydrolase activity	0.716449555827534	bayes_pls_golite062009
lipase activity	0.602417432627875	bayes_pls_golite062009
carboxylesterase activity	0.535924720022784	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.100880080935406	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [287-519]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQKFDYQHED CTGPSADRWR LLSGGPVPLS PVDLAYRFMR KAMKLFGTHS SGLHLGMSTG  60
   61 FDSGSSLDYV YQNQPQGSNA FGRLVDKIYL NSVGWRGIRQ RKTHLQILIK QAVADLHAKG 120
  121 LAVRVVDIAA GHGRYVLDAL ANEPAVSDIL LRDYSELNVA QGQEMIAQRG MSGRVRFEQG 180
  181 DAFNPEELSA LTPRPTLAIV SGLYELFPEN EQVKNSLAGL ANAIEPGGIL IYT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	14.154902
Match:	1sqfA
Description:	The crystal structure of E. coli Fmu binary complex with S-Adenosylmethionine at 2.1 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.25333584501255	bayes_pls_golite062009
transferase activity	0.999964866871553	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.644010137949015	bayes_pls_golite062009
methyltransferase activity	0.635463629299812	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	0.181420092548185	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [520-585]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GQPWHPQLEM IAGVLTSHKD GKPWVMRVRS QGEMDSLVRD AGFDKCTQRI DEWGIFTVSM  60
   61 AVRRDN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	13.09691
Match:	2ex4A
Description:	Crystal Structure of Human methyltransferase AD-003 in complex with S-adenosyl-L-homocysteine
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: