YRC Public Data Repository - Protein Structure Prediction

Protein:	YKGK_ECOLI
Organism:	Escherichia coli
Length:	196 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YKGK_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|94984662, gi\|... - gi\|94984662\|ref\|YP_604026.1\| two component LuxR family transcriptional regulator [Deinococcus geothe...	142.0	[0..12]	[195..3]
gi\|196022296, gi... - gi\|196046921\|ref\|ZP_03114142.1\| DNA-binding response regulator, LuxR family [Bacillus cereus 03BB108... gi\|228927331, gi... - gi\|228927331\|ref\|ZP_04090391.1\| DNA-binding response regulator [Bacillus thuringiensis serovar pondi... gi\|218535372, gi... - gi\|218903406\|ref\|YP_002451240.1\| DNA-binding response regulator, LuxR family [Bacillus cereus AH820]... gi\|228914867, gi... - gi\|228914867\|ref\|ZP_04078473.1\| DNA-binding response regulator [Bacillus thuringiensis serovar pulsi... gi\|227003571, gi... - gi\|227814920\|ref\|YP_002814929.1\| DNA-binding response regulator, LuxR family [Bacillus anthracis str... gi\|225864244, gi... - gi\|225864244\|ref\|YP_002749622.1\| DNA-binding response regulator, LuxR family [Bacillus cereus 03BB10... gi\|167531545, gi... - gi\|167632733\|ref\|ZP_02391059.1\| DNA-binding response regulator, LuxR family [Bacillus anthracis str.... gi\|167639661, gi... - gi\|167639661\|ref\|ZP_02397931.1\| DNA-binding response regulator, LuxR family [Bacillus anthracis str.... gi\|170669108, gi... - gi\|170687057\|ref\|ZP_02878276.1\| DNA-binding response regulator, LuxR family [Bacillus anthracis str.... gi\|170128481, gi... - gi\|170706750\|ref\|ZP_02897209.1\| DNA-binding response regulator, LuxR family [Bacillus anthracis str.... gi\|177649611, gi... - gi\|177649611\|ref\|ZP_02932613.1\| DNA-binding response regulator, LuxR family [Bacillus anthracis str.... gi\|190563758, gi... - gi\|190565731\|ref\|ZP_03018651.1\| DNA-binding response regulator, LuxR family [Bacillus anthracis Tsia... gi\|196033705, gi... - gi\|196033705\|ref\|ZP_03101116.1\| DNA-binding response regulator, LuxR family [Bacillus cereus W], gi\|... gi\|196029154, gi... - gi\|196039895\|ref\|ZP_03107198.1\| DNA-binding response regulator, LuxR family [Bacillus cereus NVH0597... gi\|49331108, gi\|... - gi\|49479552\|ref\|YP_036377.1\| response regulator [Bacillus thuringiensis serovar konkukian str. 97-27... gi\|52143191, gi\|... - gi\|52143191\|ref\|YP_083638.1\| response regulator [Bacillus cereus E33L], gi\|51976660\|gb\|AAU18210.1\| r... gi\|47527561, gi\|... - gi\|47527561\|ref\|YP_018910.1\| LuxR family DNA-binding response regulator [Bacillus anthracis str. 'Am... gi\|49185120, gi\|... - gi\|49185120\|ref\|YP_028372.1\| LuxR family DNA-binding response regulator [Bacillus anthracis str. Ste... gi\|65319569, gi\|... - gi\|65319569\|ref\|ZP_00392528.1\| COG2197: Response regulator containing a CheY-like receiver domain an... gi\|30256908, gi\|... - gi\|30262277\|ref\|NP_844654.1\| LuxR family DNA-binding response regulator [Bacillus anthracis str. Ame... gi\|254760128 - gi\|254760128\|ref\|ZP_05212152.1\| DNA-binding response regulator [Bacillus anthracis str. Australia 94... gi\|254751608 - gi\|254751608\|ref\|ZP_05203645.1\| DNA-binding response regulator [Bacillus anthracis str. Vollum] gi\|165870591, gi... - gi\|165870591\|ref\|ZP_02215245.1\| DNA-binding response regulator, LuxR family [Bacillus anthracis str.... gi\|254743522 - gi\|254743522\|ref\|ZP_05201207.1\| DNA-binding response regulator [Bacillus anthracis str. Kruger B] gi\|254737292 - gi\|254737292\|ref\|ZP_05194996.1\| DNA-binding response regulator [Bacillus anthracis str. Western Nort... gi\|254722254 - gi\|254722254\|ref\|ZP_05184042.1\| DNA-binding response regulator [Bacillus anthracis str. A1055] gi\|254684846 - gi\|254684846\|ref\|ZP_05148706.1\| DNA-binding response regulator [Bacillus anthracis str. CNEVA-9066] gi\|229265295, gi... - gi\|229600887\|ref\|YP_002866616.1\| DNA-binding response regulator, LuxR family [Bacillus anthracis str... gi\|229184493, gi... - gi\|229184493\|ref\|ZP_04311697.1\| DNA-binding response regulator [Bacillus cereus BGSC 6E1], gi\|228598... gi\|229121819, gi... - gi\|229121819\|ref\|ZP_04251039.1\| DNA-binding response regulator [Bacillus cereus 95/8201], gi\|2286616... gi\|228945885, gi... - gi\|228945885\|ref\|ZP_04108228.1\| DNA-binding response regulator [Bacillus thuringiensis serovar monte... gi\|228826031, gi... - gi\|228933571\|ref\|ZP_04096421.1\| DNA-binding response regulator [Bacillus thuringiensis serovar andal...	141.0	[0..22]	[190..1]
gi\|47557254, gi\|... - gi\|47565618\|ref\|ZP_00236658.1\| MW1789 [Bacillus cereus G9241], gi\|47557254\|gb\|EAL15582.1\| MW1789 [Ba...	141.0	[0..22]	[190..1]
gi\|196252895, gi... - gi\|196252895\|ref\|ZP_03151542.1\| two component transcriptional regulator, LuxR family [Clostridium th... gi\|67873312, gi\|... - gi\|67873312\|ref\|ZP_00503591.1\| regulatory protein, LuxR:Response regulator receiver [Clostridium the...	140.0	[0..22]	[190..2]
gi\|7471836 - pir\|\|E75450 DNA-binding response regulator - Deinococcus radiodurans (strain R1) gi\|6458715, gi\|1... - gi\|6458715\|gb\|AAF10563.1\|AE001951_3 DNA-binding response regulator [Deinococcus radiodurans R1], gi\|...	140.0	[0..22]	[195..24]
gi\|219994325, gi... - gi\|89209594\|ref\|ZP_01187989.1\| regulatory protein, LuxR:Response regulator receiver [Halothermothrix...	140.0	[0..22]	[195..2]
gi\|89156596, gi\|... - gi\|89205580\|ref\|ZP_01184149.1\| regulatory protein, LuxR:Response regulator receiver [Bacillus weihen...	140.0	[0..22]	[190..1]
gi\|89332534, gi\|... - gi\|89893086\|ref\|YP_516573.1\| hypothetical protein DSY0340 [Desulfitobacterium hafniense Y51], gi\|893...	138.0	[0..18]	[196..15]
gi\|99036997, gi\|... - gi\|99080717\|ref\|YP_612871.1\| two component LuxR family transcriptional regulator [Silicibacter sp. T...	137.0	[0..20]	[196..20]
gi\|117649430, gi... - gi\|88931302\|ref\|ZP_01136996.1\| regulatory protein, LuxR:Response regulator receiver [Acidothermus ce...	137.0	[0..22]	[195..85]

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Predicted Domain #1

Region A:
Residues: [1-196]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTWQSDYSRD YEVKNHMECQ NRSDKYIWSP HDAYFYKGLS ELIVDIDRLI YLSLEKIRKD  60
   61 FVFINLSTDS LSEFINRDNE WLSAVKGKQV VLIAARKSEA LANYWYYNSN IRGVVYAGLS 120
  121 RDIRKELVYV INGRFLRKDI KKDKITDREM EIIRMTAQGM QPKSIARIEN CSVKTVYTHR 180
  181 RNAEAKLYSK IYKLVQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	25.522879
Match:	1yioA
Description:	Crystallographic structure of response regulator StyR from Pseudomonas fluorescens
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
signal transducer activity	2.07885074402355	bayes_pls_golite062009
molecular transducer activity	2.07885074402355	bayes_pls_golite062009
transcription regulator activity	1.72455852503325	bayes_pls_golite062009
two-component response regulator activity	1.53373140048441	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: