YRC Public Data Repository - Protein Structure Prediction

Protein:	YJJW_ECOLI
Organism:	Escherichia coli
Length:	287 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YJJW_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|75239558, gi\|... - gi\|75239558\|ref\|ZP_00723528.1\| COG1180: Pyruvate-formate lyase-activating enzyme [Escherichia coli F... gi\|110346408, gi... - gi\|110644816\|ref\|YP_672546.1\| hypothetical protein ECP_4763 [Escherichia coli 536], gi\|110346408\|gb\|... gi\|91214094, gi\|... - gi\|91214094\|ref\|YP_544080.1\| hypothetical protein UTI89_C5149 [Escherichia coli UTI89], gi\|91075668\|... gi\|115515861, gi... - gi\|117626737\|ref\|YP_860060.1\| hypothetical protein APECO1_2002 [Escherichia coli APEC O1], gi\|115515...	209.0	[0..1]	[287..1]
gi\|209748918, gi... - pir\|\|D86137 probable activating enzyme yjjW [imported] - Escherichia coli (strain O157:H7, substrain... gi\|12519406, gi\|... - gi\|15804951\|ref\|NP_290993.1\| putative activating enzyme [Escherichia coli O157:H7 EDL933], gi\|125194... gi\|15834591, gi\|... - gi\|15834591\|ref\|NP_313364.1\| putative activating enzyme [Escherichia coli O157:H7], gi\|13364815\|dbj\|... gi\|168762730, gi... - gi\|189366965\|gb\|EDU85381.1\| radical SAM domain protein [Escherichia coli O157:H7 str. EC4501], gi\|16... gi\|168785022, gi... - gi\|189374932\|gb\|EDU93348.1\| radical SAM domain protein [Escherichia coli O157:H7 str. EC869], gi\|168... gi\|15834591, gi\|... - gi\|15834591\|ref\|NP_313364.1\| putative activating enzyme [Escherichia coli O157:H7 str. Sakai], gi\|13... gi\|217321348, gi... - gi\|217325127\|ref\|ZP_03441211.1\| radical SAM domain protein [Escherichia coli O157:H7 str. TW14588], ...	208.0	[0..1]	[287..1]
gi\|192926734, gi... - gi\|75256291\|ref\|ZP_00727963.1\| COG1180: Pyruvate-formate lyase-activating enzyme [Escherichia coli E... gi\|75209583, gi\|... - gi\|75209583\|ref\|ZP_00709801.1\| COG1180: Pyruvate-formate lyase-activating enzyme [Escherichia coli B...	207.0	[0..1]	[287..1]
gi\|24115609, gi\|... - gi\|24115609\|ref\|NP_710119.1\| putative activating enzyme [Shigella flexneri 2a str. 301], gi\|24054946... gi\|30043881, gi\|... - gi\|30065617\|ref\|NP_839788.1\| putative activating enzyme [Shigella flexneri 2a str. 2457T], gi\|300438... gi\|110808168, gi... - gi\|110808168\|ref\|YP_691688.1\| putative activating enzyme [Shigella flexneri 5 str. 8401], gi\|1106177...	207.0	[0..1]	[287..1]
gi\|254037390, gi... - gi\|254037390\|ref\|ZP_04871467.1\| radical SAM domain-containing protein [Escherichia sp. 1_1_43], gi\|2... gi\|188491026, gi... - gi\|75515570\|ref\|ZP_00737727.1\| COG1180: Pyruvate-formate lyase-activating enzyme [Escherichia coli 5... gi\|170021661, gi... - gi\|170021661\|ref\|YP_001726615.1\| radical SAM domain-containing protein [Escherichia coli ATCC 8739],... gi\|124499239, gi... - gi\|124530348\|ref\|ZP_01701034.1\| Radical SAM domain protein [Escherichia coli B], gi\|124499239\|gb\|EAY...	207.0	[0..1]	[287..1]
gi\|83585287, gi\|... - gi\|83585287\|ref\|ZP_00923935.1\| COG1180: Pyruvate-formate lyase-activating enzyme [Escherichia coli 1...	206.0	[0..1]	[287..1]
gi\|193070595, gi... - gi\|75234542\|ref\|ZP_00718883.1\| COG1180: Pyruvate-formate lyase-activating enzyme [Escherichia coli E...	206.0	[0..1]	[287..1]
gi\|26251268, gi\|... - gi\|26251268\|ref\|NP_757308.1\| hypothetical protein c5462 [Escherichia coli CFT073], gi\|26111701\|gb\|AA...	203.0	[0..1]	[287..1]
gi\|82779630, gi\|... - gi\|82779630\|ref\|YP_405979.1\| putative activating enzyme [Shigella dysenteriae Sd197], gi\|81243778\|gb...	203.0	[0..1]	[287..1]
gi\|157157888, gi... - gi\|75189088\|ref\|ZP_00702355.1\| COG1180: Pyruvate-formate lyase-activating enzyme [Escherichia coli E...	201.0	[0..1]	[287..1]

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Predicted Domain #1

Region A:
Residues: [1-287]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSRCALVSK IIPFSCVDGP GSRLALFLQG CNLRCKNCHN PWTMGRCNDC GECVPQCPHQ  60
   61 ALQIVDGKVV WNAVVCEQCD TCLKRCPQHA TPMAQSMSVD EVLSHVRKAV LFIEGITVSG 120
  121 GEATTQLPFV VALFTAIKND PQLRHLTCLV DSNGMLSETG WEKLLPVCDG AMLDLKAWGS 180
  181 ECHQQLTGRD NQQIKRSIYL LAERGKLAEL RLLVIPGQVD YLQHIEELAA FIKGLGDVPV 240
  241 RLNAFHAHGV YGEAQSWASA TPEDVEPLAD ALKVRGVSRL IFPALYL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.0
Match:	1tv7A
Description:	Structure of the S-adenosylmethionine dependent Enzyme MoaA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.85375915825216	bayes_pls_golite062009
transferase activity	0.885866547766734	bayes_pls_golite062009
oxidoreductase activity	0.497602428796508	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors	0.0354148694695802	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: