YRC Public Data Repository - Protein Structure Prediction

Protein:	YGED_ECOLI
Organism:	Escherichia coli
Length:	397 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YGED_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|218202668 - gi\|218202668\|gb\|EEC85095.1\| hypothetical protein OsI_32467 [Oryza sativa Indica Group] PHT44_ORYSJ - Probable anion transporter 4, chloroplastic OS=Oryza sativa subsp. japonica GN=PHT4;4 PE=2 SV=1	166.0	[0..10]	[389..179]
gi\|110827356, gi... - gi\|111615223\|ref\|ZP_01402289.1\| Sugar phosphate permease-like [Verminephrobacter eiseniae EF01-2], g...	165.0	[0..9]	[395..297]
gi\|60467752, gi\|... - gi\|60467752\|gb\|EAL65769.1\| hypothetical protein DDB0191430 [Dictyostelium discoideum], gi\|29500764\|g... gi\|60467752, gi\|... - gi\|66810832\|ref\|XP_639123.1\| major facilitator superfamily transporter [Dictyostelium discoideum AX4...	163.0	[0..15]	[367..603]
gi\|78495751, gi\|... - gi\|78495751\|ref\|ZP_00847969.1\| Major facilitator superfamily MFS_1 [Rhodopseudomonas palustris BisB1...	159.0	[0..3]	[396..440]
gi\|85110133 - gi\|85110133\|ref\|XP_963279.1\| hypothetical protein [Neurospora crassa OR74A] gi\|28924953, gi\|... - gi\|32417950\|ref\|XP_329453.1\| hypothetical protein [Neurospora crassa], gi\|28924953\|gb\|EAA34043.1\| hy...	150.0	[0..16]	[393..385]
ANTR1_ARATH - Sodium-dependent phosphate transport protein 1, chloroplastic OS=Arabidopsis thaliana GN=ANTR1 PE=1 ...	148.0	[0..10]	[392..100]
gi\|49650092 - gi\|49650092\|emb\|CAG79818.1\| YALI0E21241p [Yarrowia lipolytica] gi\|49650092, gi\|... - gi\|50553624\|ref\|XP_504223.1\| YALI0E21241p [Yarrowia lipolytica], gi\|49650092\|emb\|CAG79818.1\| unnamed...	146.0	[0..17]	[387..142]
gi\|39944294, gi\|... - gi\|39944294\|ref\|XP_361684.1\| hypothetical protein MGG_04158 [Magnaporthe grisea 70-15], gb\|EAA50399....	144.0	[0..8]	[394..131]

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Predicted Domain #1

Region A:
Residues: [1-397]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSESVHTNTS LWSKGMKAVI VAQFLSAFGD NALLFATLAL LKAQFYPEWS QPILQMVFVG  60
   61 AYILFAPFVG QVADSFAKGR VMMFANGLKL LGAASICFGI NPFLGYTLVG VGAAAYSPAK 120
  121 YGILGELTTG SKLVKANGLM EASTIAAILL GSVAGGVLAD WHVLVALAAC ALAYGGAVVA 180
  181 NIYIPKLAAA RPGQSWNLIN MTRSFLNACT SLWRNGETRF SLVGTSLFWG AGVTLRFLLV 240
  241 LWVPVALGIT DNATPTYLNA MVAIGIVVGA GAAAKLVTLE TVSRCMPAGI LIGVVVLIFS 300
  301 LQHELLPAYA LLMLIGVMGG FFVVPLNALL QERGKKSVGA GNAIAVQNLG ENSAMLLMLG 360
  361 IYSLAVMIGI PVVPIGIGFG ALFALAITAL WIWQRRH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	23.522879
Match:	1pw4A
Description:	Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transporter activity	1.47137690164233	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.29350539833585	bayes_pls_golite062009
substrate-specific transporter activity	1.27316855330085	bayes_pls_golite062009
transmembrane transporter activity	1.05831640191854	bayes_pls_golite062009
ion transmembrane transporter activity	0.0979973803429679	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: